Although the association between diabetes mellitus type 1 (T1DM) and celiac disease (CD) is well established; there are only a few studies that focus on South American children, haplotypes and their ...possible associations.
To determine the prevalence of CD markers in a group of children with T1DM and to analyze the associated clinical, immunological and genetic manifestations.
A prevalence study focusing on children with T1DM who were assessed based on variables including sociodemographics, anthropometric information, disease characteristics, laboratory results and family medical history. In partitipants a positive tTG2 (Ig A anti-transglutaminase), a duodenal biopsy and genotype were performed. The proportion of children with T1DM and CD was estimated (CI 95%). Determinations of central tendency, univariate and bivariate analysis, were also performed;
<0.05 was considered significant.
Thirteen (8.4%) of the 155 children (53.6% girls, 11.0 ±3.6 years, 2-18 years) with T1DM were tTG2 positive, four had CD (2.6%), seven had potential CD (4.5%) and nine were HLA DQ2/DQ8 positive (5.8%). Children with T1DM and CD had their last ketoacidotic episode (21.5 ±30.4 months versus 69.5 ±38.8 months,
= 0.0260) earlier than children with T1DM and potential CD. There were no differences with anthropometry or with the laboratory results regarding glycemic control.
The prevalence of CD in these children with T1DM is higher than that reported in other South American countries. The prevalence of CD was found to be associated with the time of presentation of T1DM and its main allele, the DQ2/DQ8. These findings are different from what has been described in other places around the world.
Bothersome gastrointestinal (GI) signs/symptoms, including abdominal pain, distension, nausea, and flatulence, are common in children. A diet low in fermentable oligosaccharides, disaccharides, ...monosaccharides, and polyols (FODMAPs) is frequently recommended for children with GI symptoms. Currently, there are no studies on the effect of FODMAPs in healthy schoolchildren. In this cross-sectional study, schoolchildren reported an association between FODMAPs and GI symptoms through a standardized questionnaire and images of 20 common staples known to be rich in FODMAPs. A total of 208 schoolchildren aged 8–18 years old participated. A proportion of 38.0% of children reported GI symptoms, with abdominal pain (33%) being the most common complaint followed by abdominal distension (24%) and nausea (23%). The majority of children who reported intolerances to FODMAP-containing foods were intolerant to less than two food groups (76%). While vegetables and legumes (26%), particularly black beans (11%) and onions (7%), emerged as the most common group of triggers, milk (12%) stood out as the single food most frequently associated with GI symptoms. In conclusion, there was a high prevalence of FODMAPs intolerance among schoolchildren. Larger studies are recommended to confirm these findings and to inform possible dietary interventions to reduce the effect of FODMAPs on schoolchildren.
INTRODUCTIONAlthough results show an association between the presence of generalised joint hypermobility (GJH) and functional gastrointestinal disorders (FGIDs) in children, they are limited and ...controversial. OBJECTIVETo determine the association between GJH and FGIDs and the search for risk factors for GJH in girls from a Public Educational Institution of Tuluá, Colombia. PATIENTS AND METHODSThe students completed the Rome IV Questionnaire to identify FGIDs. Each girl with a diagnosis of some FGIDs was matched with a healthy control of the same age. Joint laxity was assessed according to the Beighton score and was considered as GJH when it was ≥ 4. The prevalence of GJH was compared in girls with and without FGIDs. RESULTSOut of a total of 921 girls between 10 and 18 years of age that participated in the study, 219 (23.8%) of them had some FGIDs. The analysis was performed on a total of 169 girls with FGIDs and 169 healthy control girls. There were no significant differences in GJH between girls with and without a diagnosis of some FGIDs (OR=1.12: 95% CI; 0.71-1.77, P=.5838), nor were there any risk factors. CONCLUSIONIn this study, no relationship or any risk factor was found between GJH and the presence of FGIDs.
In this article, it is presented an unpublished work by the painter Alejo Fernández, active in Córdoba and Seville between 1497 and 1545. It shows the Burial of St Jerome and, according to different ...evidences, it belonged to the main altarpiece of the Monastery of San Jerónimo de Valparaíso (Córdoba). Likewise, various documents about the work certify that this important altarpiece was commissioned around 1503-1508 by the patrons Diego Fernández de Córdoba and Juana Pacheco to be installed in the main chapel of the monastic church. In this same place the patrons were buried together with other relatives. Finally, it has been possible to track the fortunes of the painting, which was integrated into the Spanish Gallery of Louis-Philippe, King of France, inaugurated at the Musée du Louvre in 1838.
From the 1890s, 15th and 16th century Flemish painting rediscovery generated a large-scale production of Flemish Primitives forgeries. While some of these are made using a modern support, others are ...paintings abusively restored. A certain number of these fakes found their way into Spanish collections, and even famous authors such as Chandler Post, Jacques Lavalleye and Elisa Bermejo believed them to be genuine Flemish or Hispano-Flemish works. Amongst the newly detected forgeries investigated in this contribution, some can be ascribed to the Belgian restorer and forger Joseph Van der Veken, others to the mysterious 'Valls Marín Forger'.
ABSTRACT
The HIV/AIDS infection is increasing in Latin America and the Caribbean regions, according to the World Health Organization (WHO). In Latin America, most cases are in Brasil, Mexico, and ...Colombia. Some causes of the HIV/AIDS infection in Latin America are poverty, limitations on the access to antiretroviral drugs, poor response from governmental and health authorities, migration, and scantiness of research resources. In the pediatric population, perinatal transmission is the main contact mechanism. Several digestive, hepatic, and nutritional manifestations allow the classification of HIV infection in children, according to the Centers for Disease Control and Prevention. Improvement in knowledge of the epidemiology, pathogenesis, physiopathology; and management of HIV enteropathy and on nutritional care practices of infected HIV children is recommended.
La política cultural, económica y social del franquismo vino marcada por las características ideológicas del grupo que en cada momento controlaba la agenda del régimen. En un primer periodo (1939-57) ...esta pugna se establece entre falangistas y el grupo del CSIC/Arbor. En el segundo (1957-75) contenderán para tomar las riendas el grupo falangista y los tecnócratas. Es fácil postular la continuidad de ideas, aunque con personas distintas. Entre los falangistas la realización de su revolución pendiente será la guía de acción. Más problemática es la continuidad del 2º grupo. Es posible identificar vínculos entre los tradicionalistas y la institución religiosa Opus Dei. Pero subsiste la duda sobre la existencia de una estrategia tradicionalista/Opus Dei de control del Estado que se crearía como una plataforma cultural, para más tarde convertirse en proyecto político/económico.
Introducción. La patogenia de los trastornos funcionales gastrointestinales involucra agentes infecciosos como los virus.Objetivo. Investigar el desarrollo de trastornos funcionales ...gastrointestinales en niños, a los 3, 6, 9 y 12 meses después de un episodio de dengue no grave sin signos de alarma.Materiales y métodos. Se hizo un estudio de cohorte de 73 niños con diagnóstico de dengue no grave sin signos de alarma atendidos en el Hospital Universitario del Valle “Evaristo García” y de 62 niños sanos de Cali, Colombia. Mediante el ‘Cuestionario para síntomas gastrointestinales pediátricos Roma III’ (Questionnaire for Pediatric Gastrointestinal Symptoms Rome III, QPGS-III), se determinaron los trastornos gastrointestinales funcionales a los 3, 6, 9 y 12 meses de seguimiento después de un episodio de dengue no grave sin signos de alarma. Se calcularon las medidas de tendencia central, riesgo relativo y prueba de ji al cuadrado, y se usó la prueba exacta de Fisher con un nivel de significación (p) menor de 0,05.Resultados. Se incluyeron 135 niños de 10,7±1,9 años; 51,1 % de ellos correspondía al sexo masculino y 19,3 % presentaba algún trastorno funcional gastrointestinal (9,6 % con dolor abdominal relacionado). El riesgo de presentar algún trastorno funcional gastrointestinal con dolor abdominal relacionado a los 3, 6, 9 y 12 meses de seguimiento en niños con dengue no grave sin signos de alarma fue mayor que sin dicho antecedente, pero sin diferencias significativas.Conclusión. Los resultados del estudio sugieren que el dengue no grave sin signos de alarma no incrementó el riesgo de trastornos gastrointestinales funcionales y dolor abdominal relacionado a lo largo de 12 meses de seguimiento.
PDF
