Obesity has reached worldwide epidemic proportions, adversely impacting health on a global scale. Overweight and obesity adversely impact cardiac structure and function, affecting systolic and ...diastolic ventricular function. Studies and meta-analyses have documented an obesity paradox in large heart failure cohorts, where overweight and obese individuals with established heart failure have a better short- and medium-term prognosis compared with lean patients; this relationship is strongly impacted by level of cardiorespiratory fitness. There are implications for therapies aimed at increasing lean and muscle mass, and weight loss, for the prevention and treatment of compared with in patients with concomitant obesity.
Abstract Abnormal left ventricular (LV) geometry, including LV hypertrophy (LVH), is associated with increased risk of major cardiovascular (CV) events and all-cause mortality and may be an ...independent predictor of morbid CV events. Patients with LVH have increased risk of congestive heart failure, coronary heart disease, sudden cardiac death and stroke. We review the risk factors for LVH and its consequences, as well as the risk imposed by concentric remodeling (CR). We also examine evidence supporting the benefits of LVH regression, as well as evidence regarding the risk of CR progressing to LVH, as opposed to normalization of CR. We also briefly review the association of abnormal LV geometry with left atrial enlargement and the combined effects of these structural cardiac abnormalities.
In Memoriam Arnold M Katz, MD Ventura, Hector O., MD
The American journal of cardiology,
06/2016, Letnik:
117, Številka:
12
Journal Article
Recenzirano
Arnold was honored with various research awards throughout his distinguished career, including the 1975 Humboldt Prize, the Research Achievement Award of the American Heart Association, the Peter ...Harris Distinguished Scientist Award of the International Society for Heart Research, the Lifetime Achievement Award of the Heart Failure Society of America, and the Medal of Merit of the International Academy of Cardiovascular Sciences. Throughout my medical school and my training I had always been very fond of the history of medicine and I knew all the work of Dr Katz in the field of history of heart failure.
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