We examined associations between metabolic variables and changes in coronary artery disease (CAD) in the St. Thomas' Atherosclerosis Regression Study (STARS). The course of CAD over 3 years was ...measured continually by quantitative coronary angiography, i.e., as the per patient change in the mean absolute width of coronary segments (delta MAWS). The decrease in MAWS (progression of CAD) was significantly correlated with in-trial plasma concentrations of cholesterol (P = 0.002), low-density lipoprotein (LDL) cholesterol (P = 0.001), apolipoprotein B (apoB) (P = 0.008), and lipoprotein(a) Lp(a) (P = 0.004); no significant associations were found with high-density lipoprotein (HDL) cholesterol, apoA-I, vitamin E, thyroid hormones, fibrinogen, von Willebrand factor, or post-load plasma glucose and insulin concentrations. By multiple regression analysis, LDL cholesterol was the best predictor of delta MAWS, the adjusted model explaining 22% of the variance (P = 0.04). Thus, in men with symptomatic CAD the most important metabolic predictor of change in CAD is plasma LDL cholesterol, there being no advantage in measuring other variables, in particular, apoB or Lp(a).
We aimed to examine the relationship of serum lipids, lipoproteins, apolipoproteins and antioxidants with renal dysfunction as measured by urinary excretion of albumin and of retinol binding protein ...(RBP) in insulin-dependent diabetes mellitus (IDDM). We studied 121 patients with IDDM. Glomerular function was assessed as the urinary albumin/creatinine ratio (
U
A
U
c
), and tubular function as the urinary retinol-binding protein/creatinine ratio (
U
R
U
c
), both measured in three early morning spot urine samples. The mean (range) (
U
A
U
c
) was 1.95 mg/mmol (0.3–476.5) and (
U
R
U
c
) was 17.5 μg/mmol (1.0–1853.8). 17% of the patients had a (
U
A
U
c
) > 3 mg/mmol and 33% had a (
U
R
U
c
) > 20 μg/mmol. Significant positive correlations were observed between both (
U
A
U
c
) and (
U
R
U
c
) and the following: serum total cholesterol (
P < 0.005); triglycerides (
P < 0.001); apolipoproteins A-I (
P < 0.05), A-II (
P < 0.02) and B (
P < 0.002); glycated haemoglobin (
P < 0.002). No significant associations were found with serum vitamin E, β-carotene or total antioxidant activity. In multiple regression, only (
U
A
U
c
) was independently associated with serum apo B and cholesterol concentrations. In conclusion, in IDDM glomerular dysfunction, as measured by (
U
A
U
c
), is associated with elevated serum cholesterol, triglycerides, apo B, apo A-I and apo A-II, but not with HDL cholesterol or antioxidant status. Tubular dysfunction tends to occur with increasing albuminuria, but it is not independently associated with serum lipid, lipoprotein, apolipoprotein or antioxidant levels.
OBJECTIVE
To examine the correlation between angiographie coronary artery disease (CAD) and plasma lipoprotein(a) Lp(a) concentration in non-insulin-dependent diabetes mellitus (NIDDM).
RESEARCH ...DESIGN AND METHODS
In this cross-sectional study of 36 patients with NIDDM who underwent coronary angiography, CAD was assessed visually using a coronary artery score (CAS), and plasma Lp(a) was measured immunotur-bidimetrically.
RESULTS
Lp(a) concentration was significantly higher in patients in the middle and upper tenues of CASs (>4) compared with those in the lower tenue (≤4); geometric mean 0.30 g/l(95% confidence interval CI 0.22–0.40) vs. 0.12 g/l (0.08–0.17, P = 0.002). Lp(a) was significantly and positively correlated with the CAS (R2 23%, P = 0.006), independent of other cardiovascular risk factors, including lipoprotein related variables and glycated hemoglobin.
CONCLUSIONS
Plasma Lp(a) is a strong and independent correlate of the extent of angiographie CAD in symptomatic patients with NIDDM.
Immigration to the United States soared between the 1990 and 2000 censuses and continued at high rates between 2000 and 2007, resulting in significant demographic shifts in some regions of the ...country. Most of this increase is Latino, and the region most affected is the South. A number of southern states—North Carolina, Alabama, and Georgia—reported substantial increases in their Latino populations from 1990 to 2000 (U.S. Bureau of the Census 2000a). Many saw even greater growth between 2000 and 2007. North Carolina, for example, experienced a 68.8 percent increase, from 377,084 in 2000 to 636,442 in 2007, and
Medical ethics and women Bocking, Alan D.; Burgess, Michael M.; Chance, Graham W. ...
Canadian Medical Association journal (CMAJ),
08/1990, Letnik:
143, Številka:
4
Journal Article
Unipolar pacemakers, such as the synchronous pacemaker, often produce biphasic signals which may be of considerable magnitude. Overshoot, a function of the voltage of the pacemaker, as recorded by an ...amplifying system, may be of sufficient length to completely conceal the QRS complex. Development of ventricular fibrillation may be masked, when prominent unipolar stimulus artifacts with overshoots produce essentially no change in the monitored electrocardiogram. The pacemaker signal artifact may be minimized, and the clinical danger reduced, by monitoring with lead I with an abdominal pacemaker implantation, or with lead II, III, or AVF, when the unit is placed in the axilla.
Reviews of Books Pulleyblank, Edwin G.; Hodges, Richard; Stewart, Peter ...
The International History Review,
20/6/1/, Letnik:
23, Številka:
2
Book Review
Recenzirano
MICHAEL LOEWE and EDWARD L. SHAUGHNESSY, eds. The Cambridge History of Ancient China: From the Origins of Civilization to 221 BC. New York: Cambridge University Press, 1999. Pp. xxix, 1,148. $130.00 ...(US). Reviewed by Edwin G. Pulleyblank
PEREGRINE HORDEN and NICHOLAS PURCELL. The Corrupting Sea: A Study of Mediterranean History. Oxford and Maiden, Mass.: Blackwell, 2000. Pp. xiii, 761. $34.95 (US), paper. Reviewed by Richard Hodges
JOHN ONIANS. Classical Art and the Cultures of Greece and Rome. New Haven and London: Yale University Press, 1999. Pp. xiii,306. $50.00 (US). Reviewed by Peter Stewart
GRAHAM SHIPLEY. The Greek World after Alexander, 323-30 BC. London and New York: Routledge, 2000. Pp. xxxi, 568. $29.99 (US)i paper. Reviewed by Zofia H. Archibald
MICHAEL GRANT. The Collapse and Recovery of the Roman Empire. London and New York: Routledge, 1999. Pp. xviii, 121. $30.00 (US). Reviewed by Arthur M. Eckstein
SVAT SOUCEK. A History of Inner Asia. New York: Cambridge University Press, 2000. Pp. xiii, 369. $64.95 (US), cloth; $24.95 (US), paper. Reviewed by David C. Wright
I. S. ROBINSON. Henry IV of Germany, 1056-1106. New York: Cambridge University Press, 1999. Pp. 408. $69.95 (US). Reviewed by Uta-Renate Blumenthal
WILHELM BAUM. Die Verwandlungen des Mythos vom Reich des Priesterkönigs Johannes: Rom, Byzanz und die Christen des Orients im Mittelalter. Klagenfurt: Tangenten, Verlag Kitab, 1999. Pp. 438. DM 42.00, paper. Reviewed by Bernard Hamilton
JOHN GILLINGHAM. Richard I. New Haven and London: Yale University Press, 2000. Pp. xiv, 378. $30.00 (US). Reviewed by Nick Barratt
JOHN W. O'MALLEY. Trent and All That: Renaming Catholicism in the Early Modern Era. Cambridge, Mass, and London: Harvard University Press, 2000. Pp. 219. $24.95 (US). Reviewed by Hilmar Pabel
KATHRYN BURNS. Colonial Habits: Convents and the Spiritual Economy of Cuzco, Peru. Durham and London: Duke University Press, 1999. Pp. xi, 307. $17.95 (US), paper. Reviewed by Kendall W. Brown
PAUL C. ALLEN. Philip III and the Pax Hispanica, 1598-1621: The Failure of Grand Strategy. New Haven and London: Yale University Press, 2000. Pp. xvi, 335. $35.00 (US). Reviewed by Peter O. Pierson
DANIEL M. SWETSCHINSKI. Reluctant Cosmopolitans: The Portuguese Jews of Seventeenth-Century Amsterdam. London: Littman Library of Jewish Civilization, 2000; dist. Portland: ISBS. Pp. xii, 380. $55.00 (US). Reviewed by Herman Prins Salomon
ENRIQUETA VILA VILAR and ALLAN J. KUETHE, eds. Relaciones de Poder y Comercio Colonial: Nuevas Perspectivas. Seville: Escuela de Estudios Hispano-Americanos, and Lubbock: Texas Tech University, 1999. Pp. xv, 304. PTA. 2,500. Reviewed by Christon I. Archer
FREDERICK QUINN. The French Overseas Empire. Westport: Praeger, 2000. Pp. xx, 292. $65.00 (US). Reviewed by A. S. Kanya-Forstner
JAMES SCOTT WHEELER. Cromwell in Ireland. New York: Palgrave, 1999. Pp. x, 305. $55.00 (US). Reviewed by Jane Ohlmeyer
CHRISTOPHER STORRS. War, Diplomacy, and the Rise of Savoy, 1690-1720. New York: Cambridge University Press, 1999. Pp. xiv, 345. $69.95 (US). Reviewed by Paola Bianchi
PAMELA KYLE CROSSLEY. A Translucent Mirror: History and Identity in Qing Imperial Ideology. Berkeley: University of California Press, 1999. Pp. xiv, 403. $45.00 (US). Reviewed by Susan Naquin
EDHEM ELDEM, DANIEL GOFFMAN, and BRUCE MASTERS. The Ottoman City between East and West: Aleppo, Izmir, and Istanbul. New York: Cambridge University Press, 1999. Pp. xvi, 244. $59.95 (US). Reviewed by Ira M. Lapidus
KENNETH POMERANZ. The Great Divergence: Europe, China, and the Making of the Modern World Economy. Princeton: Princeton University Press, 2000. Pp. x, 382. $39.95 (US). Reviewed by William T. Rowe
ERIK J. ZÜRCHER, ed. Arming the State: Military Conscription in the Middle East and Central Asia, 1775-1925. London and New York: I. B. Tauris, 1999; dist. New York: Palgrave. Pp. 168. $65.00 (US). Reviewed by Caroline Finkel
DORIS Y. KADISH, ed. Slavery in the Caribbean Francophone World: Distant Voices, Forgotten Acts, Forged Identities. Athens: University of Georgia Press, 2000. Pp. xxiii, 247. $35.00 (US). Reviewed by Teresita Martínez Vergne
GEOFFREY WAWRO. Warfare and Society in Europe, 1792-1914. London and New York: Roudedge, 2000. Pp. x, 246. $25.99 (US), paper. Reviewed by Keith Jeffery
KEVIN WARD and BRIAN STANLEY, eds. The Church Mission Society and World Christianity, 1799-1999. Grand Rapids and Richmond, UK: William B. Eerdmans and Curzon, 2000. Pp. xviii, 382. $45.00 (US). Reviewed by Gerald Studdert-Kennedy
REBECCA A. EARLE. Spain and the Independence of Colombia, 1810-1825. Exeter: University of Exeter Press, 2000. Pp. ix, 254. £37.50. Reviewed by David Bushnell
FERNANDO LÓPEZ-ALVES. State Formation and Democracy in Latin America, 1810-1900. Durham and London: Duke University Press, 2000. Pp. xiv, 295. $17.95 (US), paper. Reviewed by Eduardo Posada-Carbó
C. M. WOOLGAR, ed. Wellington Studies II. Southampton: Hartley Institute, University of Southampton, 1999. Pp. ix, 252. £7.50, paper; C. M. WOOLGAR, ed. Wellington Studies III. Southampton: Hardey Institute, University of Southampton, 1999. Pp. x, 300. £7.50, paper. Reviewed by John K. Severn
LUDWIG RITTER VON HÖHNEL. Over Land and Sea: Memoir of an Austrian Rear Admiral's Life in Europe and Africa, 1857-1909, ed. Ronald E. Coons and Pascal James Imperato; consulting ed. J. Winthrop Aldrich. New York and London: Holmes & Meier, 2000. Pp. xxvi, 358. $45.00 (US). Reviewed by Milan Vego
SCOTT W. MURRAY. Liberal Diplomacy and German Unification: The Early Career of Robert Morier. Westport: Praeger, 2000. Pp. xxii, 277. $65.00 (US). Reviewed by Paul Kennedy
ANDREW S. THOMPSON. Imperial Britain: The Empire in British Politics, c. 1880-1932. London and New York: Longman, 2000. Pp. xvii, 219. $79.95 (US), cloth; $27.95 (US), paper. Reviewed by Kent Fedorowich
SHOMPA LAHIRI. Indians in Britain: Anglo-Indian Encounters, Race, and Identity, 1880-1930. London and Portland: Frank Cass, 2000. Pp. xviii, 249. $59.50 (US), cloth; $24.50 (US), paper.Reviewed by Douglas A. Lorimer
ROY BRIDGES, ed. Imperialism, Decolonization, and Africa: Studies Presented to John Hargreaves: With an Academic Memoir and Bibliography. New York: Palgrave, 2000. Pp. xv, 213. $65.00 (US). Reviewed by Paul M. Canning
NANCY MITCHELL. The Danger of Dreams: German and American Imperialism in Latin America. Chapel Hill and London: University of North Carolina Press, 1999; dist. Toronto: Scholarly Book Services. Pp. xi, 312. $82.50 (CDN), cloth; $32.95 (CDN), paper. Reviewed by Reinhard R. Doerries
PAUL JULIAN WEINDLING. Epidemics and Genocide in Eastern Europe, 1890-1945. New York: Oxford University Press, 2000. Pp. xxi, 463. $159.50 (CDN). Reviewed by Sheldon Watts
J. M. ROBERTS. Twentieth Century: The History of the World, 1901 to the Present. London: Allen Lane, Penguin Press, 1999. Pp. xx, 905. £20.00. Reviewed by T. E. Vadney
MOSHE GERSHOVICH. French Military Rule in Morocco: Colonialism and Its Consequences. London and Portland: Frank Cass, 2000. Pp. xvii, 238. $57.50 (US). Reviewed by William B. Cohen
M. NAIM TURFAN. Rise of the Young Turks: Politics, the Military, and Ottoman Collapse. London and New York: I. B. Tauris, 2000; dist. New York: Palgrave. Pp. xix, 490. $69.50 (US). Reviewed by Efraim Karsh
DANIELA ROSSINI. Il mito americano nell'Italia delta Grande Guerra. Rome: Gius. Laterza & Figli, 2000. Pp. x, 284. L 50,000, paper. Reviewed by H. James Burgwyn
FREDERICK R. DICKINSON. War and National Reinvention: Japan in the Great War, 1914-1919. Cambridge, Mass.: Harvard University Asia Center, 1999; dist. Cambridge, Mass, and London: Harvard University Press. Pp. xviii, 363. $40.00 (US). Reviewed by Thomas W. Burkman
ALFRED C. MIERZEJEWSKI. The Most Valuable Asset of the Reich: A History of the German National Railway. I: 1920-1932. Chapel Hill and London: University of North Carolina Press, 1999; dist. Toronto: Scholarly Book Services. Pp. xx, 482. $123.75 (CDN). Reviewed by Andrew J. Crozier
CHRISTIAN RAITZ VON FRENTZ. A Lesson Forgotten: Minority Protection under the League of Nations: The Case of the German Minority in Poland, 1920-1934. New York: Palgrave, 2000. Pp. iii, 290. $65.00 (US). Reviewed by Carole K. Fink
MEIR ZAMIR. Lebanon's Quest: The Road to Statehood, 1926-1939. London and New York: I. B. Tauris, 2000; dist. New York: Palgrave. Pp. xii, 313. $22.50 (US), paper. Reviewed by Roger Owen
JOHN WINTON. Cunningham: The Greatest Admiral since Nelson. London: John Murray, 1998. Pp. xiv, 432. £25.00; MICHAEL SIMPSON, ed. The Cunningham Papers: Selections from the Private and Official Correspondence of Admiral of the Fleet Viscount Cunningham of Hyndhope, OM, KT, GCB, DSO and Two Bars: I: The Mediterranean Fleet, 1939-1942. Aldershot and Brookfield: Ashgate, 1999. Pp. xxvii, 634. $113.95 (US). Reviewed by Christopher M. Bell
RAY MOSELEY. Mussolini's Shadow: The Double Life of Count Galeazzo Ciano. New Haven and London: Yale University Press, 1999. Pp. x, 302. $29.95 (US). Reviewed by Alan Cassels
MACGREGOR KNOX. Common Destiny: Dictatorship, Foreign Policy, and War in Fascist Italy and Nazi Germany. New York: Cambridge University Press, 2000. Pp. xiv, 262. $27.95 (US). Reviewed by R. J. B. Bosworth
PETER NEVILLE. Appeasing Hitler: The Diplomacy of Sir Nevile Henderson, 1937-39. New York: Palgrave, 2000. Pp. xv, 237. $69.95 (US); JOHN RUGGIERO. Neville Chamberlain and British Rearmament: Pride, Prejudice, and Politics. Westport: Greenwood Press, 1999. Pp. 251. $65.00 (US). Reviewed by Neville Thompson
JOHN CORNWELL. Hitler's Pope: The Secret History of Pius XII. London: Viking, 1999. Pp. xi, 430. £20.00. Reviewed by Joseph A. Biesinger
GEOFFREY P. MEGARGEE. Inside Hitler's High Command. Lawrence: University Press of Kansas, 2000. Pp. xxi, 327. $34.95 (US). Reviewed by Earl F. Ziemke
GABRIEL GORODETSKY. Grand Delusion: Stalin and the German Invasion of Russia. New Haven and London: Yale University Press, 1999. Pp. xvi, 408. $29.95 (US)
