This timely book, which is based on the results of the Integration of the Second Generation in Europe survey, presents the disturbing results of a recent study in Stockholm that examines the ...experiences of residents descended from Turkish migrants. Focusing on three different ethno-national groups—Turks, Kurds, and Syriacs—the contributors explore issues such as identity, family situation, language use, education, labor market experiences, and employment. The essays highlight the varying degrees of success each group has achieved in the process of trying to integrate into Stockholm society. The book also examines the widespread discrimination and exclusion the descendants of migrants experience. As a whole, this volume shows a troubling picture of the obstacles faced by immigrant new societies.
This timely book presents the results of the Integration of the Second Generation in Europe survey that examines the experiences of residents of Stockholm who are descended from Turkish migrants
This volume is a study of identity processes and identity dynamics in a post-colonial, multiethnic European context that is constantly changing under the pressures of globalisation, migration ...movements and integration. The authors represent a variety of disciplines: American studies, anthropology, cultural studies, ethnology, history, social psychology and sociology. Eleven of the thirteen chapters present empirical case studies from the Netherlands, Portugal, the Basque region, Switzerland and the United Kingdom.
The accumulation of protein structural data occurs more rapidly than it can be characterized by traditional laboratory means. This has motivated widespread efforts to predict enzyme function ...computationally. The most useful/accurate strategies employed to date are based on the detection of motifs in novel structures that correspond to a specific function. Functional residues are critical components of predictively useful motifs. We have implemented a novel method, to complement current approaches, which detects motifs solely on the basis of distance restraints between catalytic residues.
ProMOL is a plugin for the PyMOL molecular graphics environment that can be used to create active site motifs for enzymes. A library of 181 active site motifs has been created with ProMOL, based on definitions published in the Catalytic Site Atlas (CSA). Searches with ProMOL produce better than 50% useful Enzyme Commission (EC) class suggestions for level 1 searches in EC classes 1, 4 and 5, and produce some useful results for other classes. 261 additional motifs automatically translated from Jonathan Barker's JESS motif set Bioinformatics 19:1644-1649, 2003 and a set of NMR motifs is under development. Alignments are evaluated by visual superposition, Levenshtein distance and root-mean-square deviation (RMSD) and are reasonably consistent with related search methods.
The ProMOL plugin for PyMOL provides ready access to template-based local alignments. Recent improvements to ProMOL, including the expanded motif library, RMSD calculations and output selection formatting, have greatly increased the program's usability and speed, and have improved the way that the results are presented.
The tension between nationalism and internationalism has been a major feature of world politics since the end of the Cold War. Based on a Nobel symposium, this collection brings together an ...international selection of acclaimed authors from a wide variety of academic disciplines. The book combines focused case studies and more theoretically based material to critically examine the post-Cold War political landscape. Subjects covered include:
changing interpretations of the nation-state and nationalism
the growing prominence of transnational organizations
technological changes in information, communication and transport
multiculturalism and citizenship
ethnicity and religious identity in African, Indian, Bosnian and Polish nationalism
the growing global significance of Islam
This outstanding volume is an invaluable resource for students of Politics and International Relations, as well as all those interested in the interplay between nationalism and internationalism in the modern world.
Globalisation, migration and integration have shaken up identity processes and identity dynamics as never before. But in a post-colonial, multi-ethnic Europe, what is identity? How is it constructed? ...Identity Processes and Dynamics in Multi-Ethnic Europe endeavours to answer these questions and more. Eleven of the thirteen chapters present empirical case studies from the Basque Country, the Netherlands, Switzerland, the United Kingdom and Portugal - thus resulting in one of the first international volumes to highlight Portugal's diverse and complex migration flows. Transnationalism also takes centre stage in several contributions that survey various types of informal and formal networks in local communities and across national borders. Via American studies, anthropology, cultural studies, ethnology, history, social psychology and sociology, the authors come from an array of disciplines as dynamic as the continent about which they write. This title is available in the OAPEN Library - http://www.oapen.org.
The purpose of this study is to describe the quantitative and qualitative findings of multiparametric prostate MRI performed after MRI-guided focal laser ablation of prostate cancer.
A total of 27 ...consenting patients met the study inclusion criteria, which included but were not limited to the presence of clinical category T1c-T2a prostate cancer with a Gleason score of 7 or less, having undergone prostate biopsy before and after focal laser ablation, and having undergone MRI before ablation, immediately after ablation, and 3 and 12 months after ablation. Signal changes were evaluated both qualitatively and quantitatively and were then correlated with the results of subsequent biopsy performed at 3 and 12 months after ablation.
MRI performed immediately after ablation revealed a hypovascular defect in the ablation zone, with patchy or bandlike decreased T2 signal most commonly noted at 3 months (in 66.7% of ablated lesions) and T2 scarring observed in most lesions (66.7%) at 12 months. Patchy or bandlike decreased apparent diffusion coefficient signal and scarlike changes were most prevalent at 3 months after ablation (50.0% of lesions), and these features remained the most commonly observed findings at 12 months after ablation (27.8% of lesions). At 12 months after ablation, 10 patients were found to have recurrent tumor, with three patients found to have persistent cancer when biopsy was performed at the ablation site. All postablation biopsy cases with positive results showed suspicious T2 and apparent diffusion coefficient characteristics, which were considered to be a well-defined nodular intermediate signal on both of these sequences. Two of the patients for whom positive biopsy findings were noted had focal enhancement of the ablation zone. A significant reduction in the forward volume transfer constant after ablation was found at the ablation site on follow-up examination.
Multiparametric MRI can reveal postablation changes in the prostate and can be a valuable tool for monitoring patients who have undergone MRI-guided focal laser ablation.
Purpose
To investigate the correlation between magnetic resonance imaging (MRI)‐derived prostate parameters and benign prostatic hyperplasia (BPH) type with the International Prostate Symptom Score ...(IPSS).
Materials and Methods
In all, 61 patients (median age, 60; range, 41–81 years) who underwent preoperative MRI and prostatectomy were included in this retrospective study. The MRI‐based parameters including total prostate volume (TPV), transition zone (TZ) volume (TZV), TZ index, intravesical prostatic protrusion (IPP), the anterior fibromuscular stroma (AFMS) distance, prostatic urethral angle, bladder wall thickness, urethral wall thickness, urethral compression, urethral wall changes, and BPH type were correlated with total IPSS, IPSS‐storage symptom (IPSS‐ss), IPSS‐voiding symptom (IPSS‐vs), and responses to the individual IPSS questions using Spearman (ρ) or Pearson (r) correlation coefficients, one‐way analysis of variance (ANOVA), and multiple linear regression.
Results
TPV (r = 0.414, P = 0.001), TZV (r = 0.405, P = 0.001), IPP (r = 0.270, P = 0.04), and AFMS distance (r = 0.363, P = 0.004) correlated with total IPSS. In multiple linear regression analysis, TZV was the only predictor for total IPSS (P = 0.001), IPSS‐ss (P < 0.001), IPSS‐vs (P = 0.03), and the scores for the IPSS questions 1 (P = 0.03) and 4 (P = 0.001). TPV was a predictor of the scores for questions 2 (P = 0.003), 3 (P = 0.009), and 7 (P < 0.001).
Conclusion
Several MRI‐derived prostate measurements (TPV, TZV, IPP, AFMS distance) correlated with total IPSS. TZV was the only predictor for total IPSS based on multiple regression analysis.
Level of Evidence: 3
J. Magn. Reson. Imaging 2017;45:917–925.
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