Objective: to determine morphological and functional characteristics of different states of fitness in adolescence rowers. Materials and methods: 21 men athletes aged from 14 to 16 years of school of ...the Olympic reserve of the city of Rostov-on-Don (RWAR) involved in rowing were examined. We used the Dorokhov R.N. technique of selection and early orientation in sports to determine the anthropometric characteristics. Following functional indicators were defined: power index of both hands, the absolute physical efficiency (APE) with the help of РWС170 test, type of vegetative regulation with the help of method of heart rate variability assessment. Results: adolescence rowers had macrosomy and micromembrane somatotype. When the condition of exercise was insufficient, the following parameters were revealed: micromesocorpulent and mesomuscular somatotype, low power index of the brush, a low value of APE, expressed vagotonic type of autonomic regulation. If the condition of exercise was satisfactory, micromesocorpulent and micromesomuscular somatotype, the average power index of the brush below the average value of APE, mild vagotonic type of autonomic regulation were registered. The highest condition of exercise was associated with microcorpulent and mesomuscular somatotype, the average power index of the brush, the average value of APE normotonic type of vegetative regulation. Conclusions: certain morpho-functional parameters as: somatotype, level of power and absolute index of physical work efficiency and autonomic regulation defined an inadequate, satisfactory or a higher state of fitness.
Objective: to determine the morphological and functional parameters of athletes-junior wrestlers, determining their specialization, qualification and training in ontogenesis. Materials and methods: ...49 male junior athletes of the school of Olympic reserve engaged in martial arts in the GrecoRoman style for 6-10 years were examined. We used the Dorokhov R.N. (1994) technique of selection and early orientation in sports to determine the anthropometric temporal characteristics. Following functional indicators were determined: absolute and relative physical performance, aerobic performance, power index eagerly, type of vegetative regulation. Results: the majority of fighters teenagers CMS had mesosomal, microcorpulent, micromesomelic, micromesic and mesomacromembral somatotype. A comprehensive study of the functional parameters of the wrestlers showed that indicators of absolute and relative physical performance were higher in young men CMS and were respectively 1318.6±149.5 kg∙m/min and 19.3±2.5 kg∙m/(min∙kg). Aerobic performance was higher in adolescents and first-rank sportsmen: 51.8±9.36 ml/(min∙kg). The strength indices of the hands were higher in the young men's CMS and contributed to 70.6±6.37% for the right hand and 66.08±12.1% for the left hand, which was explained by the component body composition of the body of young men. Most of the wrestlers revealed moderate parasympathicotonia and amphotonic. Conclusions: the R.N. Dorokhova and V.G. Petrukhina (1994) method of somatotyping allows to differentiate athletes, involved in martial arts in the Greco-Roman style, into 3 levels of variation: dimensional, component and proportion and to determine their specialization, qualification and degree of training in ontogenesis.
Laser lithotripsy using optical fiber to fragment salivary gland stones (sialoliths) is currently one of the most successful methods for treating salivary stone disease. It is important to reduce the ...fragmentation time of extremely hard salivary stones, which in practice is more than three hours in the case of large stones. We present new approaches to lithotripsy related to the use of radiation from a nanosecond thulium-doped fiber laser at a wavelength of 1.94 μm. The study is performed using gypsum phantoms and sialoliths. Parameters of laser exposure are determined that provide a high rate of lithotripsy without significant heating of surrounding tissues. It is shown that the mechanism of action of nanosecond laser radiation, which is well absorbed in water upon fragmentation of stones, is associated with the burnout of the binding organic material of sialolite and the explosive boiling of water. The results obtained can serve as the basis for the development of new promising medical technology.
Currently, enhancement of doctoral education performance is becoming one of the central tasks for state policy in the field of science and education. In 2013
–
2015 Russian doctoral education ...experienced radical transformations aimed to increase the performance of doctoral programs and enhance the quality of dissertations. First, doctoral education moved towards the structured (educational) model. Second, norms and rules of the work of dissertation boards changed significantly. The purpose of this study is to explore how these reforms affected the performance of doctoral education. The empirical base for the study comprises the data on dissertations defense of graduates of 2018 at 12 Russian universities (N=1022), which were collected by the authors using the web scraping technique. The main findings obtained from the analysis of these data are threefold. First, time-to-degree has increased with most of the dissertations now being defended only after the completion of the programs. Second, in social sciences, this delay of defense has intensified abnormally (80% of dissertation in this field are defended after the program completion). Third, the actual performance, i.e., one that takes into account dissertations defended after the program completion, has decreased significantly in social sciences and humanities. These results show that the traditional practice to evaluate performance based on the proportion of graduates who defend their dissertations during the normative period of time does not reflect the reality. To made adequate managerial decisions regarding doctoral education, it is necessary to arrange the monitoring of dynamics of dissertations that are defended after the program completion both on institution and state levels.
Compound (7-NH
3
-L)
2
B
10
H
10
has been prepared and identified by elemental analysis and IR and UV spectroscopies. This compound as a potential inhibitor of free radicals and contains a ...representative of coumarins possessing biological activity and a representative of boron cluster anions widely used in various fields of science and technology. The radiation-chemical transformations of 7-amino-4-methylcoumarin in CH
3
CN, 96% C
2
H
5
OH, in the CH
3
CN/CF
3
COOH system, and in 20% aqueous solution (H
3
O)
2
B
10
H
10
have been first studied by UV spectroscopy.
As Russian and international experience shows, the massification of doctoral education is not only a driver of socio-economic development, but also a significant challenge for national policy in the ...field of higher education and research. The increase in demand for doctoral studies can lead to an enormous decrease in the quality of training unless particular measures for quality assurance and support are implemented. There are dozens of such practices worldwide. In this article, we consider three of them: 1) diversification of doctoral programs; 2) collaboration with industry and business; and 3) improving the quality of supervision. These practices have not yet been implemented in Russian doctoral programs on a systemic level. However, we believe that they are the most relevant and potentially useful for the Russian context, as they can improve the efficiency of doctoral training in terms of the number and quality of defenses, as well as increase the level of graduates’ preparation for the labor market.
Foot-and-mouth disease (FMD) is classified by the World Organization for Animal Health (OIE) as a Schedule A disease. Given the potential for rapid spread of the disease, all suspected cases should ...be reported and investigated immediately. Understanding the mechanism of FMD spread and control measures is key to outbreak investigation and allows the source of an outbreak to be traced along with potential routes of further spread. Foot-and-mouth disease is endemic in vast areas of Africa, Asia and South America. In 2022, the following countries remain unfavorable for FMD: Kazakhstan, Mongolia, China, Israel, Indonesia, UAE, Palestine, Algeria, Botswana, Zambia, Zimbabwe, Malawi, Mozambique, Tunisia, South Africa. In Russia, in 2022, foot and mouth disease was not registered. There are seven serotypes of foot-and-mouth disease virus: O, A, C, Asia 1, SAT 1, SAT 2 and SAT 3. Cattle, buffalo, sheep, pigs, goats, African buffalo, deer, yaks and other artiodactyls are susceptible to it. The two principle ways in which an animal can become infected are by inhalation of virus particles in the air, and by ingestion of food material containing virus particles, also through abrasions, contaminated instruments or artificial insemination. Up to 50 % of ruminant animals become persistently infected after clinical recover and termed a "carrier". Key risk factors for virus introduction are the introduction of a new animal into the herd with an unknown FMD vaccination status, seasonality, lack of vaccination, herd size. The cause of infection is often the uncontrolled or illegal movement of livestock. The main risk of FMD introduction comes from livestock, vehicles, people directly working with livestock susceptible to FMD, wild animals. The key principles of biosecurity are isolation of sick animals, cleaning and disinfection of premises and equipment. Foot-and-mouth disease is a major barrier to international trade in livestock and animal products, so countries free of the disease are taking increased precautions to prevent the virus from entering.
If missingness is encountered in a categorical regressor, which approach is preferable: complete case analysis or the missing-indicator method? The former approach implies including in analysis ...(linear regression in our research) only the cases without missingness across analyzed variables. This approach is embedded in many statistical applications by default, and despite the opinion that its applicability is rather restricted, up-to-date studies provide evidence for its wide applicability – even to missingness not at random. The missing-indicator method, according to which missing data are replaced with a single valid value and a new missing-indicator variable is created, pretends to be an alternative that keeps a full sample available for analysis and, hypothetically, does not lead to the deterioration of parameter estimates. By means of simulated data and a statistical experiment, controlling the factors of missingness mechanism, missingness proportion, and a regression model's specification, we compare parameter estimates produced by each approach to handling missingness – how biased and inefficient they are. According to the results, no approach leads to crucially biased estimates, but the missing-indicator method produces ineffective estimates.
To study the peculiarities of carrying clinically significant allelic variants of TPMT and DPYD genes associated with the response to drug therapy in cancer practice among 9 ethnic groups of the ...Russian Federation.
The study included 1446 conditionally healthy volunteers from 9 ethnic groups. Carriage of polymorphic TPMT and DPYD gene markers was detected by the Real-Time PCR (polymerase chain reaction) method.
In all ethnic groups, the distribution of genotypes and alleles matched the equilibrium of Hardy-Weinberg. TPMT*3A (rs1800460) and TPMT*3C (rs1142345) were observed in heterozygous state in all investigated ethnic groups. In the Kabardinian group (n=204) the frequency of the TPMT*3A minor allele (MAF, %) was 2.94%; Balkars (n=200) 1.25%; Ossetians (n=239) 1.67%; Chuvashes (n=238) 1.89%: Mari (n=206) 1.21%; Tatars (n=141) 1.77%; Russians (n=134) 4.85%. The frequency of the TPMT*3C minor allele (MAF, %) in the Kabardinian group (n=204) MAF was 4.90%; Balkars (n=200) 1. 75%; Buryats (n=114) 0.44%; Ossetians (n=239) 1.88%; Chuvashes (n=238) 1.68%: Mari (n=206) 1.21%; Tatars (n=141) 1.42%; Russians (n=134) 4.48%. The results of the analysis of DPYD*2A polymorphism (rs3918290) demonstrated ethnic peculiarities of distribution. In the heterozygous state it was found only in the groups of Kabardins (n=204, MAF 1.22%), Balkars (n=200, MAF 2.00%), and Ossetians (n=239, MAF 0.63%).
The results obtained in the study will be useful for developing personalized algorithms of antitumor therapy in cancer practice, including those aimed at increasing the safety of chemotherapy.
EU-Armenia: all is not lost? Zhuchkova, Yulia V.; Miroshnikov, Sergey N.
Vestnik Tomskogo gosudarstvennogo universiteta. Istorii͡a,
12/2017
50
Journal Article
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