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  • In vitro antibody-mediated ... In vitro antibody-mediated SARS-CoV-2 infection suppression through human ACE2 receptor blockade
    Redd, Priscilla S.; Merting, Alyssa D.; Klement, John D. ... Immunology letters, August 2024, 2024-08-00, 20240801, Letnik: 268
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    •Monoclonal antibody 4G8C11 exhibits stable and high affinity for human ACE2 receptor.•4G8C11 blocks SARS-CoV-2 and variant binding to human ACE2.•4G8C11 has no significant inhibitory activity ...
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  • Angiotensin‐converting enzy... Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)
    Bourgonje, Arno R; Abdulle, Amaal E; Timens, Wim ... The Journal of pathology, July 2020, Letnik: 251, Številka: 3
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    Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus responsible for the current ...
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  • Composition and divergence ... Composition and divergence of coronavirus spike proteins and host ACE2 receptors predict potential intermediate hosts of SARS‐CoV‐2
    Liu, Zhixin; Xiao, Xiao; Wei, Xiuli ... Journal of medical virology, June 2020, Letnik: 92, Številka: 6
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    From the beginning of 2002 and 2012, severe respiratory syndrome coronavirus (SARS‐CoV) and Middle East respiratory syndrome coronavirus (MERS‐CoV) crossed the species barriers to infect humans, ...
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  • Organ‐protective effect of ... Organ‐protective effect of angiotensin‐converting enzyme 2 and its effect on the prognosis of COVID‐19
    Cheng, Hao; Wang, Yan; Wang, Gui‐Qiang Journal of medical virology, July 2020, Letnik: 92, Številka: 7
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    This article reviews the correlation between angiotensin‐converting enzyme 2 (ACE2) and severe risk factors for coronavirus disease 2019 (COVID‐19) and the possible mechanisms. ACE2 is a crucial ...
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  • Little to no expression of ... Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages
    Song, Xiang; Hu, Wei; Yu, Haibo ... Cytometry. Part A, February 2023, Letnik: 103, Številka: 2
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    Angiotensin‐converting enzyme‐2 (ACE2) has been recognized as the binding receptor for the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). Flow cytometry demonstrated that there was ...
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  • Cell entry mechanisms of SA... Cell entry mechanisms of SARS-CoV-2
    Shang, Jian; Wan, Yushun; Luo, Chuming ... Proceedings of the National Academy of Sciences - PNAS, 05/2020, Letnik: 117, Številka: 21
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    A novel severe acute respiratory syndrome (SARS)-like coronavirus (SARS-CoV-2) is causing the global coronavirus disease 2019 (COVID-19) pandemic. Understanding how SARS-CoV-2 enters human cells is a ...
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  • Structural bases for the hi... Structural bases for the higher adherence to ACE2 conferred by the SARS‐CoV‐2 spike Q498Y substitution
    Erausquin, Elena; Glaser, Fabian; Fernández-Recio, Juan ... Acta crystallographica. Section D, Structural biology, September 2022, Letnik: 78, Številka: 9
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    A remarkable number of SARS‐CoV‐2 variants and other as yet unmonitored lineages harbor amino‐acid substitutions with the potential to modulate the interface between the spike receptor‐binding domain ...
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