Himmelstraße 55 in Grinzing belonged to the topography of Canetti's Vienna just as much as the Ferdinandstraße. Canetti was often a guest of Ernst Benedikt, the editor of the Neue Freie Presse, at ...whose house he met Friedl Benedikt (1916-53) for the first time, Ernst Benedikt's daughter, and her three sisters, Gerda, Ilse and Susanne. The future life of Friedl Benedikt (Anna Sebastian) was in many respects determined by her relationship with Canetti. Drawing on many still unpublished letters by the four sisters which they exchanged between Vienna, Zurich, London, Paris, Stockholm and New York from 1937 to 1985, the article traces their paths through exile and emigration. The letters reveal an image of Viennese life transported to alien climes.
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Zur Topografie von Canettis Wien gehörte neben der Ferdinandstraße auch die Himmelstraße 55 in Grinzing. Canetti war regelmäßig Gast bei Ernst Benedikt, dem Herausgeber der Neuen Freien Presse. Hier traf Canetti erstmals Friedl Benedikt (1916-1953), Ernst Benedikts Tochter, und ihre drei Schwestern Gerda, Ilse und Susanne. Die Beziehung zu Canetti war für Friedl Benedikt (Anna Sebastian) in vielerlei Hinsicht lebensentscheidend. Anhand vieler noch unpublizierter Briefe der vier Schwestern zwischen Wien, Zürich, London, Paris, Stockholm und New York von 1937 bis 1985 werden die Wege der Schwestern Benedikt in der Emigration nachgezeichnet. In den Briefen wird das Bild des Lebens im Exil und eines in die Fremde ausgelagerten Wien sichtbar.
The article presents the collection of contrafacta preserved in the archive of the abbey and parish church of St Daniel in Celje. It provides an overview of the models used, the modes and outcomes of ...the transformations and the possible position of the repertoire in the cultural space of Celje in the first half of the nineteenth century.
This review offers a contemporary clinical approach to the recognition, prevention and management of sarcopenia, and discusses recent clinically relevant advances in the aetiopathogenesis of muscle ...ageing that may lead to future therapeutic targets.
The key recent directions for sarcopenia are in the diagnosis, understanding molecular mechanisms and management. Regarding the recognition of the condition, it has become increasingly clear that different definitions hamper progress in understanding. Therefore, the Global Leadership in Sarcopenia has been established in 2022 to develop a universally accepted definition. Moreover, substantial work is occurring to understand the various roles and contribution of inflammation, oxidative stress, mitochondrial dysfunction and metabolic dysregulation on skeletal muscle function and ageing. Finally, the role of resistance-based exercise regimes has been continually emphasised. However, the role of protein supplementation and hormone replacement therapy (HRT) are still under debate, and current clinical trials are underway.
With the global ageing of our population, there is increasing emphasis on maintaining good health. Maintenance of skeletal muscle strength and function are key to preventing frailty, morbidity and death.
Purpose of review The purpose of this review is to summarise the recent developments in trial readiness, natural history studies, and interventional clinical trials for Becker muscular dystrophy ...(BMD). Recent findings As several treatment concepts have claimed to convert patients with Duchenne muscular dystrophy (DMD) into a BMD phenotype, BMD itself has moved into the focus of clinical research. Natural history studies have helped to better characterize patients with BMD and the disease is now a target for interventional trials. In parallel, there have been advances in diagnostics and in the development of preclinical models. Summary Despite increased collaborative efforts to improve trial readiness amongst patients with BMD, there is still a lack of long-term natural history data, and the broad spectrum of disease severity remains a challenge for well designed clinical trials.
Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common myopathies, involving over 870,000 people worldwide and over 20 FSHD national registries. Our purpose was to summarize the main ...objectives of the scientific community on this topic and the moving trajectories of research from the past to the present.
To date, research is mainly oriented toward deciphering the molecular and pathogenetic basis of the disease by investigating DUX4-mediated muscle alterations. Accordingly, FSHD drug development has been escalating in the last years in an attempt to silence DUX4 or to block its downstream effectors. Breakthroughs in the field include the awareness that new biomarkers and outcome measures are required for tracking disease progression and patient stratification. The need to develop personalized therapeutic strategies is also crucial according to the phenotypic variability observed in FSHD subjects.
We analysed 121 literature reports published between 2021 and 2023 to assess the most recent advances in FSHD clinical and molecular research.
The article discusses the narrative strategies in Benedikt Livshits's One and a Half-Eyed Archer, in which one can distinguish, conditionally speaking, a “Gogolian” and a “Tolstoyan” principle. This ...determines the portraiture, in a more or less positive or negative light, of various major Futurists, such as David Burliuk, Aleksei Kruchenykh, Velimir Khlebnikov, Vladimir Maiakovskii, and other figures, such as Elena Guro, Igor' Severianin and Nikolai Kul'bin.
Članak donosi istraživanje benediktinskoga Pravila pod vidom svetopisamskih tekstova. Matejevo evanđelje sačinjava okosnicu Pravila. Najviše tekstova pojavljuje se iz 5 - 7 poglavlja. Ova su ...poglavlja poznata kao Isusov “Govor na gori” ili “Magna charta” Novoga Zavjeta. Tekstovi iz spomenutih poglavlja određuju status Isusovih učenika u Zajednici. Pravilo sačinjava i određenu sintezu biblijske antropologije potkrepljujući svoja načela evanđeoskim direktnim i indirektnim navodima. To je dokaz želji Utemeljitelja da se monaški duhovni život zasniva isključivo na Isusovim riječima. Istraživanje Pravila pod vidim evanđeoskih tekstova pokazalo se velikim doprinosom i benediktinskoj zajednici.
The article presents a research of the Benedictine Rule under the light of biblical texts. The Gospel of Matthew forms the backbone of the Rule. Most texts come from 5 - 7 chapters. These chapters are known as Jesus' "Speech on the Mount" or the "Magna Charta" of the New Testament. The texts from the mentioned chapters determine the status of Jesus' disciples in the Congregation. The Rule also constitutes a certain synthesis of biblical anthropology, supporting its principles with direct and indirect references from the Gospel. This is proof of the Founder's desire that monastic spiritual life should be based exclusively on the words of Jesus. The research of the Rule under the light of the Gospel texts proved to be a great contribution to the Benedictine community as well.
Autor u ovom radu najprije ističe da je u povijesti istraživanja monaškoga života i duhovnosti u ranome kršćanstvu krjepost poslušnosti ostala izvan fokusa. Zato svoje istraživanje uvodi tumačeći ...teološko značenje ove krjeposti u kontekstu ranokršćanskog asketizma i monaštva. Potom prelazi na propitivanje ove krjeposti u konkretnom povijesnom kontekstu monaških inicijativa u zapadnome kršćanstvu od 4. do 6. stoljeća. U tom smislu najprije istražuje značenje ove krjeposti za sv. Jeronima, potom za sv. Augustina i naposljetku za sv. Benedikta. S obzirom na sv. Jeronima i njegov pristup monaštvu, istaknuo je da je Jeronim preferirao zajednički život preporučujući ga kao pouzdaniji jer pretpostavlja posluh starijima. Sveti Augustin pak kao autor najstarijeg monaškog pravila na Zapadu definira posluh i jednim poglavljem svoga Pravila. I premda ne ulazi u detalje, ipak je očit napredak da je Hiponac Pravilom istaknuo posluh kao nezaobilaznu krjepost monaškoga života. Kao krunu ovoga procesa autor ističe značenje sv. Benedikta i njegova Pravila u kojem posluh ima svoje mjesto kao jedna od najznačajnijih krjeposti. A za kraj donosi završni uvid u pristup posluhu od vremena sv. Jeronima do vremena sv. Benedikta, jasno dokazujući da su upravo ova trojica promicatelja monaštva na Zapadu uložili veliki napor u afirmaciji poslušnosti za monaški život.
In this paper the author first points out that in the history of research into monastic life and spirituality in early Christianity, the virtue of obedience remained out of focus. That is why he introduces this research by interpreting the theological meaning of this virtue in the context of early Christian asceticism and monasticism. Then he moves on to the analysis of this virtue in the concrete historical context of monastic initiatives in Western Christianity from the 4th to the 6th century. In this sense, he first explores the meaning of this virtue for St. Jerome, then for St. Augustine and finally for St. Benedict. Regarding St. Jerome and his approach to monasticism, he points out that Jerome preferred communal life, recommending it as more reliable because it assumes obedience to elders. Saint Augustine, on the other hand, as the author of the oldest monastic rule in the West, defines obedience in one chapter of his Rule. And although he does not go into details, it is still an obvious progress that, by his Rule, Bishop of Hippo emphasized obedience as an indispensable virtue of monastic life. As the crown of this process, the author emphasizes the importance of St. Benedict and his Rule in which obedience has its place as one of the most important virtues. And lastly, he brings a final view on the approach to obedience from the time of St. Jerome until the time of St. Benedict, clearly proving that it was these three promoters of monasticism in the West who made a great effort in affirming obedience for the monastic life.