Globally, there are now over 160 million confirmed cases of COVID-19 and more than 3 million deaths. While the majority of infected individuals recover, a significant proportion continue to ...experience symptoms and complications after their acute illness. Patients with ‘long COVID’ experience a wide range of physical and mental/psychological symptoms. Pooled prevalence data showed the 10 most prevalent reported symptoms were fatigue, shortness of breath, muscle pain, joint pain, headache, cough, chest pain, altered smell, altered taste and diarrhoea. Other common symptoms were cognitive impairment, memory loss, anxiety and sleep disorders. Beyond symptoms and complications, people with long COVID often reported impaired quality of life, mental health and employment issues. These individuals may require multidisciplinary care involving the long-term monitoring of symptoms, to identify potential complications, physical rehabilitation, mental health and social services support. Resilient healthcare systems are needed to ensure efficient and effective responses to future health challenges.
Throughout the Covid‐19 pandemic, we have become used to seeing daily numbers of cases and deaths go up and down. But in some countries, the reported numbers show very little movement over days and ...weeks – they are “underdispersed”, says Dmitry Kobak, and this may be a sign that all is not right with the data
Throughout the Covid‐19 pandemic, we have become used to seeing daily numbers of cases and deaths go up and down. But in some countries, the reported numbers show very little movement over days and weeks – they are “underdispersed”, says Dmitry Kobak, and this may be a sign that all is not right with the data.
OBJECTIVES
The objective was to compare COVID‐19 outcomes in the Omicron‐driven fourth wave with prior waves in the Western Cape, assess the contribution of undiagnosed prior infection to differences ...in outcomes in a context of high seroprevalence due to prior infection and determine whether protection against severe disease conferred by prior infection and/or vaccination was maintained.
METHODS
In this cohort study, we included public sector patients aged ≥20 years with a laboratory‐confirmed COVID‐19 diagnosis between 14 November and 11 December 2021 (wave four) and equivalent prior wave periods. We compared the risk between waves of the following outcomes using Cox regression: death, severe hospitalisation or death and any hospitalisation or death (all ≤14 days after diagnosis) adjusted for age, sex, comorbidities, geography, vaccination and prior infection.
RESULTS
We included 5144 patients from wave four and 11,609 from prior waves. The risk of all outcomes was lower in wave four compared to the Delta‐driven wave three (adjusted hazard ratio (aHR) 95% confidence interval (CI) for death 0.27 0.19; 0.38. Risk reduction was lower when adjusting for vaccination and prior diagnosed infection (aHR: 0.41, 95% CI: 0.29; 0.59) and reduced further when accounting for unascertained prior infections (aHR: 0.72). Vaccine protection was maintained in wave four (aHR for outcome of death: 0.24; 95% CI: 0.10; 0.58).
CONCLUSIONS
In the Omicron‐driven wave, severe COVID‐19 outcomes were reduced mostly due to protection conferred by prior infection and/or vaccination, but intrinsically reduced virulence may account for a modest reduction in risk of severe hospitalisation or death compared to the Delta‐driven wave.
BACKGROUND:Medical mistrust, a result of systemic racism, is prevalent among Black Americans and may play a role in COVID-19 inequities. In a convenience sample of HIV-positive Black Americans, we ...examined associations of COVID-19 related medical mistrust with COVID-19 vaccine and COVID-19 treatment hesitancy, and negative impacts of COVID-19 on antiretroviral therapy (ART) adherence.
METHODS:Participants were 101 HIV-positive Black Americans (ageM=50.3 years; SD=11.5; 86% cisgender male; 77% sexual minority) enrolled in a randomized controlled trial of a community-based ART adherence intervention in Los Angeles County, CA. From May to July 2020, participants completed telephone interviews on negative COVID-19 impacts, general COVID-19 mistrust (e.g., about the government withholding information), COVID-19 vaccine and treatment hesitancy, and trust in COVID-19 information sources. Adherence was monitored electronically with the Medication Events Monitoring System.
RESULTS:Nearly all participants (97%) endorsed at least one general COVID-19 mistrust belief, and over half endorsed at least one COVID-19 vaccine or treatment hesitancy belief. Social service and healthcare providers were the most trusted sources. Greater COVID-19 mistrust was related to greater vaccine and treatment hesitancy b (SE)=0.85 (0.14), p<.0001 and b (SE)=0.88 (0.14), p<.0001, respectively. Participants experiencing more negative COVID-19 impacts showed lower ART adherence, assessed among a subset of 49 participants b (SE) = -5.19 (2.08), p = .02.
DISCUSSION:To prevent widening health inequities, healthcare providers should engage with communities to tailor strategies to overcome mistrust and deliver evidence-based information, in order to encourage COVID-19 vaccine and treatment uptake.
Long-term complications of COVID-19 Desai, Amar D; Lavelle, Michael; Boursiquot, Brian C ...
American Journal of Physiology: Cell Physiology,
01/2022, Letnik:
322, Številka:
1
Journal Article
Recenzirano
Odprti dostop
SARS-CoV-2 has rapidly spread across the globe and infected hundreds of millions of people worldwide. As our experience with this virus continues to grow, our understanding of both short-term and ...long-term complications of infection with SARS-CoV-2 continues to grow as well. Just as there is heterogeneity in the acute infectious phase, there is heterogeneity in the long-term complications seen following COVID-19 illness. The purpose of this review article is to present the current literature with regards to the epidemiology, pathophysiology, and proposed management algorithms for the various long-term sequelae that have been observed in each organ system following infection with SARS-CoV-2. We will also consider future directions, with regards to newer variants of the virus and their potential impact on the long-term complications observed.
Resumen:Desde los últimos años del tercer mandato de Hugo Chávez la República Bolivariana de Venezuela se encuentra atravesando una profunda crisis política, económica y social, la cual ha provocado ...una salida masiva de población venezolana hacia el exterior recrudecida por la crisis sanitaria del Covid-19. Uruguay, con una política migratoria flexible, se ha convertido en un destino ventajoso a la hora de obtener la documentación necesaria para residir y trabajar en igualdad de condiciones con la población nacional. El acceso al mercado laboral se ha tornado en la principal meta de estos migrantes y refugiados ya que este les permite acceder a la vivienda, la salud y al sistema financiero. Su acceso presenta particularidades vinculadas a las necesidades del mercado laboral uruguayo y a la calificación presentada por los migrantes y refugiados, analizada desde una perspectiva teórica por teorías como la de los mercados duales. En este artículo presentamos los resultados obtenidos de una investigación mixta realizada, entre 2018 y 2022, sobre la experiencia migratoria laboral de los migrantes y refugiados venezolanos en Uruguay.
O processo de registro de marca no Brasil é realizado pelo Instituto Nacional de Propriedade Industrial (INPI). Muitos empresários não registram as suas marcas, muitas das vezes por não conhecerem ...como o processo funciona. A pandemia de covid-19 trouxe novas oportunidades de negócios, o que pode ter influenciado no pedido de registro da marca pelas empresas. Com o objetivo de realizar um mapeamento do registro de marcas no Brasil e os efeitos causados pela pandemia de covid-19, foi realizado um levantamento das informações contidas no site do INPI, na área “estatística e estudos econômicos”, nas seções “estatística” e “relatórios” ao longo de 2014 a 2021. Os resultados mostraram que o número de pedido de registro de marca no INPI cresceu ao longo dos anos de 2014 a 2021, sendo impulsionado durante a pandemia. Conclui-se que o pedido de registro de marca e sua concessão no Brasil está em crescimento e que a pandemia de covid-19 não afetou o pedido de registro de marca dos residentes, porém afetou dos não residentes. Entretanto, ainda há muitos pedidos não concedidos, o que pode ser reflexo da falta de informação e acompanhamento do processo de pedido de registro de marca.
Editorial Moraes, Joysi
Revista Pensamento Contemporâneo em Administração,
01/2023, Letnik:
17, Številka:
1
Journal Article
Recenzirano
Odprti dostop
Efeitos do treinamento em liderança em funcionarios de uma rede supermercadista: evidencias de um experimento de campo (Effects of leadership training on employees of a supermarket chain: evidence ...from a field experiment), de Neuza Lobato Rodrigues Vieira, Luciana Carvalho de Mesquita Ferreira, Samir Lotfi Vaz e Athos Carlos Silva, a partir de uma pesquisa junto a 100 gestores e 300 operadores em 10 das 23 lojas de um grupo lojista de faturamento na casa dos R$3 bilhöes, além de 750 consumidores, evidenciam que lojas que receberam treinamento nao apresentam desempenho superior quando comparadas as lojas que nao receberam. Sentidos do trabalho para maes trabalhadoras (Home queen? Acomodaçöes colaborativas: análise dos fatores determinantes na predisposiçao a reutilizaçao do serviço (Collaborative accomodations: analysis of the determinant factors in the predisposition to reuse the service), de José Lucas Silva Siqueira e Renata Francisco Baldanza, buscaram compreender as relaçoes entre determinantes do compartilhamento de acomodaçao e a predisposiçao a reutilizaçao desse serviço via Airbnb.
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