In recent years, the attention of the librarian world aimed at the progress of Linked Open Data technology and Wikimedia projects has focused on Wikidata, whose infrastructure has proved to be ...perfectly compatible with Wikicite, an initiative that aims to build a vast database of bibliographic references in linked open data. As part of this initiative, many projects originate from collaborations between the Wikimedia Foundation and libraries: the Library of the University of Salerno also actively participated in the initiative, including the bibliographic metadata of the journal Bibliothecae.it. It is the first italian example of corpus related to a scientific periodical of bibliographicbiblioteconomical scope entirely loaded in Wikidata. The project allows the use of data in any project or program that uses the LOD technology, in order to facilitate the interchange between cultural resources and satisfy the information needs of the user. In the area of bibliography and librarianship, this action represents a new way of creating and sharing bibliographic data, of doing information retrieval and of conducting bibliometric analysis. The positive effects of the project concern the wiki community, which needs reliable and verified sources to base its contents, and the scientific community: by openly publishing the citations sets, an enormous graph of scientific knowledge is opened, encouraging the dissemination, publication and open evaluation of research results.
JudaicaLink is a novel resource which provides a knowledge base of Jewish culture and history. It is based on multilingual domain-specific information from encyclopedias and general-purpose knowledge ...bases such as The Integrated Authority File (GND) of the German National Library. JudaicaLink can be used for contextualization of metadata, i.e., entity resolution within and linking of metadata to improve resource access and to provide richer context to the user. Many resources for contextualization, particularly specialized resources for the given domain, are only available in unstructured form. General-purpose resources like DBpedia are hard to use due to their sheer size while only a very small subset of the data is actually relevant. Therefore, JudaicaLink aims at integrating relevant subsets of various data sources to function as a single hub for the contextualization process. JudaicaLink is freely available on the Web as Linked Open Data. In this paper, we explain how JudaicaLink is built, how it can be accessed by users, as well as its architecture, technical implementation, applications and relations to Jewish culture.
This paper is focused to address the map display usability for finding given POI addresses in a popular urban city area. LOD 1 of 3D representations of city buildings are presented into a 2.5D map ...for pedestrian navigation test. This 3D map display is evaluated against familiar 2D map system on the test participants’ smartphones. 16 participants were involved in the field test. The typical walking model of a searching task that is focused only to look for a certain address of building is chosen as the way finding model during the field test. Three kinds of navigation processes i.e. self-orientation, spatial knowledge acquisition and navigation decision for searching task were evaluated for each test participant. Usability measures of 3D map-based display over 2D-map based display for pedestrian navigation were collected from test participants’ mobile devices. In addition to that, activities of test participants in terms of acceleration and orientation information are used to support analysis of pattern and trends of test participants. As the testing app is also intended to support smart city application, its ability to provide user report on complaints was also assessed. Most participants agreed with the statements in the questionnaire that were organized into three sections, i.e. addressing participants’ interaction, participants’ responses in navigation processes and crowdsensing. The results suggest that 3D map-based pedestrian navigation is more usable to be used to look for a certain address of building in central tourist area of urban city.
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•New Schiff base 1,3-bis({(4-oxo-4H-chromen-3-yl)methylideneamino})urea (CCH) has been synthesized and characterized.•Probe CCH showed a visual colorimetric response from colorless to ...yellow for Cu2+ ions, exceptionally.•Synthesized Schiff base CCH efficiently detect pNT with negligible interference of other nitroaromatics taken for study.
A new chromone based Schiff base probe 1,3-bis({(4-oxo-4H-chromen-3-yl)methylideneamino})urea (CCH) has been synthesized in one step by the condensation reaction between 3-formylchromone and carbohydrazide in a 2:1 M ratio. The characterization of CCH was done by employing various analytical techniques; FTIR, 1H NMR, 13C NMR, HRMS and FESEM. The probe CCH showed a naked eye colorimetric response from colourless to yellow for the Cu2+ ions with greater selectivity over other metal ions taken for analysis. The binding constant and limit of detection of CCH for Cu2+ ions were calculated to be 4.5 × 105M−1 and 11.4 × 10−7M, respectively, using UV–Visible titrations. The DFT (Density functional theory) results also confirmed the experimental studies. In addition, CCH has shown its applicability for the detection of nitroaromatic compound i.e., p-nitrotoluene (pNT). The sensing mechanism of pNT was studied by UV–Visible and fluorescence studies. A significant quenching of the emission intensity of CCH at 402 nm in the case of pNT was noted above other nitroaromatics taken for study. The binding constant and limit of detection for pNT were calculated to be 1.2 × 105 M−1 and 25 × 10−9M, respectively, using B-H plot. The presence of other nitroaromatics negligibly affects the detection of pNT in CCH solution, as confirmed by anti-interfering studies. FESEM analysis of CCH with pNT confirmed the formation of an adduct. The time resolved fluorescence lifetime measurement also ensured the CCH-pNT adduct formation and the average life time data revealed that the quenching process was dynamic. The CCH-pNT adduct formation was also validated via DFT studies. Overall results suggested that the Schiff base CCH could be an efficient option to detect Cu2+ ions colorimetrically and pNT by fluorimetrically.
Fluorescent probe 1 gave LODs of 0.046 and 0.10 pM for Cu2+ and F− detections, respectively.
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•A new bis(fluorenyl-triazole)-conjugated naphthoquinoline-dione probe (1) was prepared in ...two steps.•The fluorescence emission of probe 1 was effectively quenched upon Cu2+ addition.•In situ-prepared 1-Cu2+ complex exhibited selective ‘Turn-On’ fluorescence upon addition of F−.•Probe 1 gave an LOD = 0.046 pM for Cu2+ detection, while its Cu2+ complex showed LOD = 0.010 pM for F− detection.•Photo-induced electron transfer (PET) is mainly responsible for the fluorescence quenching.
Wide usage of Cu2+ and F− in various industries and their potential hazard toward human health necessitate the development of a probe for their selective and sensitive detection. While various probes have been invented for the respective detection of these two ions, there are few probes allowing for their simultaneous or sequential detection. The current study introduces a naphthoquinoline-dione probe (probe 1) that contains two fluorenyl-triazole units conjugated to the probe aromatic core via an amine functional group. Fluorescence emission of the probe was selectively quenched upon addition of Cu2+ among various metal ions, and the resulting probe 1-Cu2+ complex displayed ‘Turn-On’ fluorescence upon addition of F−. Over the course of this cascade detection, the calculated LODs of the probe were 0.046 (Cu2+) and 0.10 pM (F−). The effective fluorescence quenching and restoration (i.e., cascade detection) observed were enabled by the strong binding of Cu2+ to the probe and a subsequent dissociation of this metal ion from the probe due to the presence of F−, respectively. The ‘ON and OFF’ luminescence observed in the solution state of the probe was reproduced when probe 1, which was absorbed on solid supports, was used for detection. These results were replicable when the solid-supported probe 1 was used to sense Cu2+ or F− from various real samples such as urine (Cu2+) and dental care solution (F−). Based on these results, we built an “ON-OFF-ON” molecular switch and fabricate a molecular logic circuit with a memory unit.
A new dipicolinimidamide based receptor, N,N’-(pyridine-2,6-diyl)dipicolinimidamide receptor AM2 is designed for the recognition of Cu2+ among all cations with high selectivity investigated in ...aqueous solutions via synergistic effects of intermolecular hydrogen bonding and electrostatic interactions. The photophysical properties of the AM2 receptor were tested by UV/Visible absorption methods. The binding method was completely confirmed by computer based studies. Theoretical statistics have highlighted the role of π-π stacking and hydrogen bonding in binding of Cu2+ with receptor AM2. Receptor AM2 selectively recognized Cu2+ in EtOH/water with a detection limit down to 3.49 μM and can be utilized to recognize Cu2+ ions in real samples.
•A dipicolinimidamide based receptor, N,N’-(pyridine-2,6-diyl)dipicolinimidamide receptor AM2 which serves as a chemosensor for Cu2+ ions.•AM2 is successfully utilized in the preparation of test strips and supported silica, which is relevant to detecting Cu2+ ions in a 100% aqueous environment.•Pyridine substituted thiourea derivative.•Low detection and quantification limit.
In this paper, we construct a new combined multiscale finite element method to solve the elliptic problem which has both a highly oscillating diffusion coefficient and a very complicated boundary. To ...design a numerical method for this kind of problems is difficult because that the microscopically geometrical information of the boundary and oscillation information of the coefficient should be taken into account simultaneously, which usually requires a very fine mesh. The main idea of the proposed method is to adopt unfitted fine scale meshes on the complicated boundary by using the cut finite element, and adopt the coarse scale meshes for the other part by using the recently developed local orthogonal decomposition (LOD) technique. Through this way, the introduced method can deal with arbitrarily complex boundaries and cut down some unnecessary computational effort. To ensure that the discrete systems are well-posed, we utilize the penalty technique on the artificial interface between coarse and fine meshes as well as on the boundary. The ghost penalty technique is used on the boundary to avoid the ill-condition of the system matrix. The error estimate and the condition number of the system matrix for the proposed method are derived without any periodic assumptions on the coefficient and boundary shape. Especially, the result is independent of the way that the boundary cut the mesh. Numerical experiments further confirm the theoretical results and demonstrate the accuracy and efficiency of the proposed method.
•SARS-CoV-2 pandemic has outpaced developing diagnostic assays.•Multiple molecular assays were developed for the detection of SARS-CoV-2.•Altona, the CDC assay, and GenMark are compared.
In December ...2019, a novel coronavirus (SARS-CoV-2) was first isolated from Wuhan city, China and within three months, the global community was challenged with a devastating pandemic. The rapid spread of the virus challenged diagnostic laboratories to rapidly develop molecular diagnostic methods. As SARS CoV-2 assays became available for testing on existing molecular platforms, laboratories devoted unprecedented energy and resources into evaluating the analytical performance of the new tests and in some cases developed their own diagnostic assays under FDA-EUA guidance. This study compares the validation of three different molecular assays at the Johns Hopkins Molecular Virology laboratory: the RealStar® SARS-CoV-2 RT-PCR, ePlex® SARS-CoV-2, and the CDC COVID-19 RT-PCR tests. Overall, our studies indicate a comparable analytical performance of the three assays for the detection of SARS-CoV-2.
Terrestrial Laser Scanning (TLS) is an efficient and reliable method for collecting point clouds which have a range of applications in the Architecture, Engineering and Construction (AEC) domain. To ...ensure that the acquired point clouds are suitable to any given application, data collection must guarantee that all scanning targets are acquired with the specified data quality, and within time limits. Efficiency of data collection is important to reduce jobsite activity disruptions. Effective and efficient laser scanning data collection can be achieved through a prior planning optimisation process, which can be called Planning for Scanning (P4S). In the construction domain, the P4S problem has attracted increasing interest from the research community and a number of approaches have been proposed.
This manuscript presents a systematic review of prior P4S works in the AEC domain and presents a categorisation of point cloud data quality criteria. The review starts with the identification and grouping in three categories of the point cloud data quality criteria that are commonly considered as constraints to the P4S problem. The three categories of data quality criteria include 1) completeness, 2) accuracy and spatial resolution, and 3) ‘registrability’. The prior P4S works are then reviewed in a structured way by contrasting them in the way they formulate the P4S optimisation problem: the type of inputs they assume (model and possible scanning locations), the constraints they consider, and the algorithm they utilise to solve the optimisation problem. This work makes two contributions: (1) it identifies gaps in knowledge that require further research such as the need to establish a fully automated scan plan which provides the optimum coverage in construction domain specifically for indoor construction; and (2) it provides a framework — principally a set of criteria — for others to compare new P4S methods against the existing state of the art in the field. This will not only be valuable for young researchers who want to start research in solving the P4S problem, but also for the ones already working in the domain to rethink the problem from different perspectives.
•We review of need for planning for (laser) scanning (P4S) in construction.•We propose to categorise point cloud quality measures in 3 groups.•The groups are: completeness, accuracy, and registrability.•We compare prior P4S works based on inputs, constraints, and solving algorithms.•We identify gaps in knowledge to be considered for future research.
Quercetin possesses low solubility and decreases oral bioavailability. One way to increase the bioavailability of quercetin is by formulating a self-nanoemulsifying drug delivery system (SNEDDS). In ...vitro dissolution testing of SNEDDS needs to be carried out using a validated analytical method. This study aims to validate the quercetin analytical method in in vitro dissolution testing. Validation was carried out with two solvents, namely hydrochloric acid buffer pH 1.2 (HCl-1,2) and phosphate buffer pH 6.8 (PO-6.8). It tested some parameters, including linearity, detection limit (LoD), quantification limit (LoQ), accuracy, and precision. The quercetin calibration curve for both solvents has a value of r≥0.999. The LoD at HCl-1,2 and PO-6,8 were 0.26 ppm and 0.27 ppm, respectively. The LoQ of HCl-1,2 and PO-6,8 were 0.86 ppm and 0.91 ppm, respectively. The percentage recovery in both solvents was in the range of 80-110%. The relative standard deviation of the two solvents was less than 7.3%. The quercetin analytical method has been successfully validated as indicated by the results of linearity, detection limit, quantification limit, accuracy, and precision that met the requirements
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