Voltage imaging was first conceived in the late 1960s and efforts to find better organic voltage sensitive dyes began in the 1970s and continue until today. At the beginning it was difficult to ...measure an action potential signal from a squid giant axon in a single trial. Now it is possible to measure the action potential in an individual spine. Other chapters will discuss advances in voltage imaging technology and applications in a variety of biological preparations. The development of genetically encoded voltage sensors has started. A genetically encoded sensor could provide cell type specific expression and voltage recording (see Chap. 20). Optimizing the signal-to-noise ratio of an optical recording requires attention to several aspects of the recording apparatus. These include the light source, the optics and the recording device. All three have improved substantially in recent years. Arc lamp, LED, and laser sources are now stable, more powerful, and less expensive. Cameras for recording activity have frames rates above 1 kHz and quantum efficiencies near 1.0 although they remain expensive. The sources of noise in optical recordings are well understood. Both the apparatus and the noise sources are discussed in this chapter.
El Síndrome de Melkersson-Rosenthal es una entidad rara caracterizada por edema granulomatoso orofacial, episodios de parálisis facial y lengua plegada. La presentación monosintomática de labios se ...denomina queilitis granulomatosa de Miescher. Clásicamente se ha tratado con múltiples medicamentos con respuesta parcial o insatisfactoria, por lo que el tratamiento ideal es el quirúrgico, que obtiene resultados permanentes y permite al paciente relaciones interpersonales satisfactorias. Sin embargo la corrección propuesta por los diferentes autores disminuye el grosor del labio a expensas de dejar un estigma de deformidad de labio "ondulado" ya que no se acorta el labio en sentido transverso y únicamente se adelgaza. El presente artículo describe el tratamiento propuesto para corregir esta deformidad mediante la resección en bloque del tercio medio del labio superior. Además hace referencia a la afectación del cuello en el caso que presentamos, no descrita en la bibliografía actual al respecto, que daba al paciente un aspecto de cuello de "iguana", y que fue corregida mediante resección en huso y liposucción.Melkersson-Rosenthal Syndrome is a rare entity characterized by granulomatous orofacial swelling, recurrent facial palsy and lingua plicata. It's monosyntomatic form affecting only lips is known as Miescher granulomatous cheilitis. Many conservative treatments have been proposed to resolve the swelling; however many times they present recurrence or fail to respond. The surgical correction permit permanent improvement and better appearance. The surgical posterior reduction cheiloplastry removing mucosa and submucosa all along the lip proposed by several authors, gives the lips an stigma of the " ruffle" aspect; this is because there is no shortening of the total length of the previously enlarged lip because of the granulomatous swelling. We report the correction of this deformity by total thickness resection of the middle third of the lip which resolve this deformity. In this patient, we also report the involve of the neck which gave him the deformity of "iguana neck", resolved by direct resection and liposuction. The neck involvement in this pathology was not previously reported in the literature.
Se for bem-sucedida e permitir ao "NYT" no medio prazo manter o alto custo da producao de um jornalismo realmente bem-feito, com reportagens originais e muitos "furos" (daqueles capazes de levar os ...governos e a sociedade para um estagio melhor do que o anterior), reportagens bem escritas, fotografadas, filmadas, infografadas, editadas, apresentadas e por fim distribuidas da maneira que o publico gostar, maravilha. Se for malsucedida, bem... sua solucao nao sera copiada mundo afora. Rosental Alves e carioca e foi diretor de Redacao do "Jornal do Brasil". Explico para os mais jovens: o "Jornal do Brasil" foi um dos mais importantes jornais brasileiros, antes de mudar de gestao e declinar em circulacao a ponto de extinguirem a versao impressa e transformarem-no meramente em um endereco na internet que, temo, seja traco em audiencia na medicao do Ibope. Ou seja, o "JB" acabou. Ou esta agonizando em praca publica.
Melkersson-Rosenthal syndrome (MRS) is an uncommon granulomatous condition characterized by persistent or recurrent orofacial oedema, relapsing facial paralysis and fissured tongue. We report here a ...case of MRS with the classical triad of signs accompanied by unilateral anterior uveitis. A 35-year-old man with a fissured tongue, recurrent facial palsy and orofacial oedema presented with a 3-month history of conjunctival redness and decreased vision in the right eye. On evaluation of visual acuity, the patient was only able to count fingers. Slit lamp examination revealed severe conjunctival injection, cells and flare, posterior synechiae and keratic precipitates. Examination of the left eye revealed no evidence of inflammation. Examination of the other systems was normal. The patient was treated with topical corticosteroids and cycloplegics and the visual acuity improved to 7/10. To our knowledge, there are no previous reports of an association between uveitis and MRS.
This was the message given by Finance Minister Avraham Shochat and Tourism Minister Amnon Lipkin-Shahak at the cabinet meeting yesterday. Lipkin-Shahak explained that many of the small-scale ...entrepreneurs, such as those offering rooms for rent adjacent to their homes, had seen the previously rosy situation as an opportune time to take out loans to expand their facilities. According to the CBS, there was a similar drop of 43% in the number of overnight stays by tourists in local hotels in comparison with October last year, and there were even 9% fewer overnight lodgings by Israelis in the same comparative periods. According to the Hotel Association, overall combined number of bed nights by foreign tourists and Israelis in local hotels reached 1.3 million in October of this year, 29% less than during October 1999.
Provider: - Institution: - Data provided by Europeana Collections- Rosental, Gingkobaum; um 1950.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 ...1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Rosental, Gingkobaum; um 1950.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 ...1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Rosental, Büste Fechner-Denkmal; 1942.- All metadata published by Europeana are available free of restriction under the Creative ...Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
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