Gene Expression database of Normal and Tumor tissues 2 (GENT2) is an updated version of GENT, which has provided a user-friendly search platform for gene expression patterns across different normal ...and tumor tissues compiled from public gene expression data sets.
We refactored GENT2 with recent technologies such as Apache Lucene indexing for fast search and Google Web Toolkit (GWT) framework for a user-friendly web interface. Now, GENT2 contains more than 68,000 samples and has several new useful functions. First, GENT2 now provides gene expression across 72 different tissues compared to 57 in GENT. Second, with increasing importance of tumor subtypes, GENT2 provides an option to study the differential expression and its prognostic significance based on tumor subtypes. Third, whenever available, GENT2 provides prognostic information of a gene of interest. Fourth, GENT2 provides a meta-analysis of survival information to provide users more reliable prognostic value of a gene of interest.
In conclusion, with these significant improvements, GENT2 will continue to be a useful tool to a wide range of researchers. GENT2 is freely available at http://gent2.appex.kr .
Survival analysis and Generalized Estimating Equation (GEE) models were used to assess the association between the biomarkers and the outcomes. On multivariable analysis using the GEE model (see ...Table 1), higher ALT and higher AST were associated with mortality after adjustment for sex, BMI, age, albumin, and platelets. In the time-to-event analysis, the Kaplan Meier curves showed that APRI >1 could be a potential predictor of mortality (P = 0.0729 see Figure 1).
Introduction: Achalasia is a motility disorder of the esophagus due to loss of peristalsis of the lower esophagus and failure of LES(Lower esophageal sphincter) to relax causing dysphagia.The most ...common surgical technique used to treat achalasia is called the Heller Myotomy (HM), which is the gold standard. Per-oral esophageal Myotomy (POEM) is a novel endoscopic technique that has gained considerable traction over the past decade. Survival analysis was done where unadjusted and adjusted hazard ratio was calculated.
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