The outcomes of this study revealed the importance of recruiting local Native American tribal community members as participants in an Adult Facilitator Trainee Program for a cultural based ...intervention, Intertribal Talking Circle (ITC), that addresses prevention of substance use among Native American youth. Survey results indicate that Native-Reliance (cultural identity) and self-efficacy increased among the trainees from base-line to 3-months post the training session. Themes emerged from qualitative interviews conducted with the participants that described their readiness to implement and sustain the Talking Circle intervention program within their tribal communities after the research project was completed.
Association is very important to explore and find identity for teenagers, but socialization is also vulnerable to mental threats in the form of insecurity that disturbs the future of teenagers. With ...this research, it is hoped that it can overcome or at least minimize the impact of youth insecurity due to association, so that the prospective youth of the nation's golden generation can avoid prolonged mental illness. Based on the background of this writing, the formulation of the research problem is obtained, namely: 1) How much influence does the association have on adolescent insecurity? 2) What are the patterns of causes and what are the forms of adolescent insecurity in the association?. This study was designed with the aim of explaining and answering the questions in the focus of the research above with the emphasis on: 1) Knowing the magnitude of the influence of association on the emergence of a sense of insecurity in adolescents. 2) State and explain the pattern of causes of insecurity in the association. With this research, researchers can find out in depth about the correlation between association and insecurity in adolescents.
To achieve real-time health monitoring in civil engineering, a FBG acceleration sensor with asymmetric shaped flexible hinge structure is proposed. Combined with the theoretical analysis, the ...expressions of resonance frequency and sensitivity are deduced, and the effects of the structural parameters of the sensor on the resonance frequency and sensitivity are analyzed and simulated. Based on the optimization results, a fiber Bragg grating acceleration sensor was designed and fabricated. The amplitude-frequency response, linear sensitivity response, and lateral anti-interference ability were tested experimentally. The experimental data shows a sensor resonance frequency of 350 Hz, a sensitivity of 90.96 pm/g, and a linear correlation of 99.59%. These results closely align with the theoretical predictions of a resonance frequency of 344 Hz, and a sensitivity of 98 pm/g, confirming the accuracy of the sensor's theoretical analysis.The transverse interference immunity of the sensor is 3.7%, and an operating frequency band of 10–250 Hz. It indicates that the sensor is promising for medium and low frequency vibration measurement.
•A FBG acceleration sensor based on a asymmetric flexible hinge structure is proposed.•The sensitivity of the sensor is 90.96 p.m./g, and the operating frequency range is 10–250 Hz.•The lateral immunity in the y-axis working direction is only 3.7%.•The sensors has small size of 48 × 16*40 mm.
Rolling circle amplification (RCA) is a widely used DNA amplification method that uses circular template DNA as input and produces multimeric, linear single- or double-stranded DNA. Circle-to-circle ...amplification (C2CA) has further expanded this method by implementing product recircularization using restriction and ligation, leading to a higher amplification yield and enabling the generation of circular products. However, C2CA is a multistep, nonisothermal method, requiring multiple fluid manipulations and thereby compromises several advantages of RCA. Here, we improved C2CA to implement a one-pot, single step, isothermal reaction at temperatures ranging from 25 to 37 °C. Our C2CAplus method is simple, robust, and produces large quantities of product DNA that can be seen with the naked eye.
In this paper, we consider the fixed-circle problem on metric spaces and give new results on this problem. To do this, we present three types of F C -Khan type contractions. Furthermore, we obtain ...some solutions to an open problem related to the common fixed-circle problem.
In this article the complete description of the decisions of a functional equation(1 + ¯ζeiθ z)pf (z) = f (ω(0))f (z)is given, where ω(z) = (eiθ z + ζ )/(1 + ¯ζeiθ z) – automorphism of a unit circle ...E and the decisions are searched among analytical in E functions. It is established, that research of a given functional equation is closely connected to property of stationary points of automorpism ω(z).
Šiame darbe pilnai išspręsta funkcionalinė lygtis(1 + ¯ζeiθ z)pf (z) = f (ω(0))f (z),kur ω(z) = (eiθ z + ζ )/(1 + ¯ζeiθ z) yra vienetinio skritulio analizinis automorfizmas.
Abstract Although microfluidic systems have been important tools in analytical chemistry, life sciences, and medical research, their application was rather limited for drug-screening and biosensors. ...Here, we described a microfluidic device consisting of a multilayer micro-channel system that represented the hemodynamic cerebral vascular system. We analyzed wall shear stresses related to aneurysm formation in the circle of Willis (CoW) and their morphological variations using this system. This device was controlled by pneumatic valves, which occluded various major arteries by closing the associated channels. The hemodynamic analysis indicated that higher degrees of shear stress occurred in an anterior communicating artery (ACoA), particularly in the hypoplastic region of the posterior communicating artery (PCoA) and the P1 segment. Furthermore, occlusion of a common carotid artery (CCA) or a middle cerebral artery (MCA) increased the shear stress, whereas occlusion of a vertebral artery (VA) decreased the shear stress. These results indicate that the morphological variation of the CoW may affect aneurysm formation resulting from increased wall shear stress. Therefore, the technique described in this paper provides a novel method to investigate the hemodynamics of complex cerebral vascular systems not accessible from previous clinical studies.
Endovascular mechanical thrombectomy (EVMT) has shown significant efficacy in improving neurological functions in patients with intracranial internal carotid artery occlusion (IICAO), but its ...clinical outcomes are variable. We examined the relationship between favorable clinical outcomes after EVMT in IICAO and a set of predictors.
In this retrospective study, 189 patients with IICAO treated by EVMT at 3 centers from November 2015 to December 2020 were included and analyzed. Non-contrast computed tomography and computed tomography angiography were evaluated on admission. The morphology of IICAO was categorized into Ia, Ib, L, or T types, depending on the involvement of the posterior communicating artery origin, proximal anterior cerebral artery, and middle cerebral artery. The Willis' circle was categorized as integrated or compromised Willis' circle. In combination with the involvement of the IICAO and the integrity of Willis' circle, we used the primary collateral grade (PCG) to describe the presence of functional Willisian collaterals. Baseline data including demographics, characteristics, vascular risk factors, and initial National Institutes of Health Stroke Scale scores were collected. Hemorrhagic transformation was evaluated using the 24-hour non-contrast computed tomography after EVMT. Favorable outcomes based on modified Rankin scale, were defined as 0–2 at 90 days.
A total of 189 patients were included (median age, 69 years; 126 male 66.7%). 104 patients 55.0% showed reperfusion after EVMT, but 72 patients 38.1% achieved favorable outcomes at 90 days. The mortality rate of type Ib was significantly higher than that with type Ia (χ2 = 14.21, P = 0.001). The outcome with different structure of Willis' circle was not statistically different between the 2 groups. A multivariate logistic regression analysis showed that IICAO T-type (odds ratio, 0.028 95% confidence interval: 0.323–3.829, P = 0.042) and PCG 2 (odds ratio 9.42795% confidence interval:1.863–47.698, P = 0.007) were predictors of favorable outcomes.
Evaluation of PCG by determining the type of IICAO and the integrity of Willis' circle may serve as a valuable indicator for the prognosis and as an essential reference for screening patients before EVMT.
High latitude ionospheric density structures such as polar cap patches and arcs are capable of deflecting high frequency (HF) radio waves to off‐great circle paths, and are likely detrimental to ...technologies dependent on HF radio propagation. In this study, nearly 2.5 years of 4.6–14.4 MHz data from a multi‐frequency HF radio link between Qaanaaq, Greenland and Alert, Canada are used to investigate high‐latitude off‐great circle propagation in the polar cap. After an example of HF radio propagation affected by polar cap patches is shown in detail, a statistical analysis of the occurrence and impacts of off‐great circle deflections in the polar cap is presented. Off‐great circle propagation is shown to be increasingly common with increasing frequency up to 11.1 MHz, such that averaged over 1 year, received 11.1 MHz signals experienced deflections >30° from the great circle direction 65.6% of the time. The occurrence of these deflections across the year is shown to be at a maximum in the winter, while occurrence across the day varies with season. Trends across both time of day and time of year for 11.1 and 14.4 MHz deflections are consistent with polar cap patch occurrence trends. Off‐great circle deflections are shown to be associated with increased time‐of‐flights, a larger range of positive and negative Doppler shifts, increased Doppler spreads, and lower signal‐to‐noise ratios. These results are discussed in the context of ionospheric phenomena in the polar cap, and implications for over‐the‐horizon radars operating at high latitudes.
Plain Language Summary
High frequency (HF) radio waves can travel long distances by bouncing between the ground and the ionosphere; an upper layer of the Earth's atmosphere, allowing them to be used for communications and surveillance in remote locations. However, strong space weather can change the paths these radio waves take, causing problems for HF radio technologies. In this paper, radio transmissions sent between Qaanaaq, Greenland and Alert, Canada are studied in order to better understand how often HF radio waves are deflected by space weather at high latitudes, and what effect these deflections have on the signals themselves. After a brief example of what space weather deflections look like, transmissions sent over a whole year are studied to determine how deflections depend on radio frequency, time of day, and time of year. Then, the effects these deflections have on other signal properties is studied. It is found that deflections are very common at high latitudes, especially in the winter. Deflections tend to increase the travel time of signals, change their frequency, and reduce their signal strength. These results are shown to be connected to polar cap patches and arcs; which are common space weather phenomena near the poles.
Key Points
Off‐great circle propagation occurring in the polar cap is studied using years of data from an HF radio link in the polar cap
Large (greater than 30°) deflections from the great circle are shown to be very common, especially in the winter
These deflections are shown to affect HF radio signals in ways that are consistent with interactions with polar cap patches and arcs
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