Nanotechnology in cosmetics Katz, Linda M.; Dewan, Kapal; Bronaugh, Robert L.
Food and chemical toxicology,
11/2015, Letnik:
85
Journal Article
Recenzirano
Nanomaterials are being used in cosmetic products for various effects. However, their use also raises potential safety concerns. Some of these concerns can be addressed by determining the type of ...nanomaterials used, as well as stability, potential for skin absorption, route of exposure, and how they are formulated in cosmetic products. There has been considerable effort internationally to harmonize approaches in order to address definitional issues and safety concerns related to the use of nanomaterials in cosmetic products.
•Nanomaterials are being used in cosmetic products for various effects.•The definition of nanomaterials is still evolving.•There has been considerable effort internationally to harmonize approaches in order to address definitional issues and safety concerns related to the use of nanomaterials in cosmetic products.
The production of drugs, cosmetics, and food which are derived from plant cell and tissue cultures has a long tradition. The emerging trend of manufacturing cosmetics and food products in a natural ...and sustainable manner has brought a new wave in plant cell culture technology over the past 10 years. More than 50 products based on extracts from plant cell cultures have made their way into the cosmetics industry during this time, whereby the majority is produced with plant cell suspension cultures. In addition, the first plant cell culture-based food supplement ingredients, such as Echigena Plus and Teoside 10, are now produced at production scale. In this mini review, we discuss the reasons for and the characteristics as well as the challenges of plant cell culture-based productions for the cosmetics and food industries. It focuses on the current state of the art in this field. In addition, two examples of the latest developments in plant cell culture-based food production are presented, that is, superfood which boosts health and food that can be produced in the lab or at home.
Cosmetics can contain harmful compounds such as heavy metals. Several metals have a cumulative effect on the body, especially fatty tissues, and may have different health effects on the human body ...over the long term. Therefore, the main objective of this study was to assess the health risks of heavy metals in cosmetics in Iran. Also, in this study, Monte Carlo simulation was used to investigate uncertainties. In this study, heavy metals data of cosmetics were extracted from studies carried out at intervals 2010–2018. International and Iranian databases such as Google Scholar, Web of Science, Springer, Science Direct, PubMed, Scopus, Irandoc, Magiran, Scientific Information Database (SID), and Information Institute for Scientific (ISC) were searched for this purpose. In this study, the index of the Margin of Safety was calculated to determine the risk of human contact with metallic impurities in cosmetic products used by humans. In the selected period, 11 studies were conducted on the measurement of heavy metals in cosmetics in Iran. In these studies, cosmetics such as eye shadow, eye pencil, powder, cream, and lipstick were studied. The Margin of Safety (MoS) values calculated for different metals were higher than the established safe standard by WHO. The highest and lowest amount of systemic exposure dosage in all types of cosmetic investigated (lipstick, cream, eye pencil, face powder, and eye shadow) was related to Fe and Hg. The mean hazardous quotient (HQ) for Cd, Cr, Ni, Cu, Mn, Zn, Pb, and Hg was 1.05E-03, 1.03E-01, 7.95E-03, 2.59E-03, 1.05E-03, 4.98E-03, 7.22E-04, 1.85E-01, and 1.35E-05, respectively. The highest HQ (6.10E-01) was found for Pb, which was observed in the cream.
The Threshold of Toxicological Concern (TTC) is an important risk assessment tool which establishes acceptable low-level exposure values to be applied to chemicals with limited toxicological data. ...One of the logical next steps in the continued evolution of TTC is to develop this concept further so that it is representative of internal exposures (TTC based on plasma concentration). An internal TTC (iTTC) would provide threshold values that could be utilized in exposure-based safety assessments. As part of a Cosmetics Europe (CosEu) research program, CosEu has initiated a project that is working towards the development of iTTCs that can be used for the human safety assessment. Knowing that the development of an iTTC is an ambitious and broad-spanning topic, CosEu organized a Working Group comprised a balance of multiple stakeholders (cosmetics and chemical industries, the EPA and JRC and academia) with relevant experience and expertise and workshop to critically evaluate the requirements to establish an iTTC. Outcomes from the workshop included an evaluation on the current state of the science for iTTC, the overall iTTC strategy, selection of chemical databases, capture and curation of chemical information, ADME and repeat dose data, expected challenges, as well as next steps and ongoing work.
The threshold of toxicological concern (TTC) has been used for the safety assessment of packaging migrants and flavouring agents that occur in food. The approach compares the estimated oral intake ...with a TTC value derived from chronic oral toxicity data for structurally-related compounds. Application of the TTC approach to cosmetic ingredients and impurities requires consideration of whether route-dependent differences in first-pass metabolism could affect the applicability of TTC values derived from oral data to the topical route. The physicochemical characteristics of the chemical and the pattern of cosmetic use would affect the long-term average internal dose that is compared with the relevant TTC value. Analysis has shown that the oral TTC values are valid for topical exposures and that the relationship between the external topical dose and the internal dose can be taken into account by conservative default adjustment factors. The TTC approach relates to systemic effects, and use of the proposed procedure would not provide an assessment of any local effects at the site of application. Overall the TTC approach provides a useful additional tool for the safety evaluation of cosmetic ingredients and impurities of known chemical structure in the absence of chemical-specific toxicology data.
The cosmetics industry is one of the most dynamically developing sectors globally, and Europe has the largest share of that market. In Poland, the cosmetics industry is one of the most significant ...economic segments. Currently, natural cosmetics remain a strongly developing sector of the cosmetics industry. The increasing self-awareness of consumers and the omnipresent trend of being "eco" influence the increased interest in natural cosmetics. The development of the natural cosmetics market is confirmed by the increasing production and growing willingness of consumers to purchase this type of product.
The study analysed the purchase frequency and the type of cosmetic products consumers choose. The most recognised natural cosmetics brands and certificates confirming their naturalness were also analysed. Additionally, the purchase preferences of consumers choosing natural cosmetics and those not in this category were examined. The focus was on factors affecting the choice of different cosmetic products.
The study was conducted as an anonymous survey of 24 questions (19 single-choice and five multiple-choice questions). Volunteers participated in the study regardless of gender, age, occupation, or income. The survey questionnaires were conducted using Google Forms through a shared link. The study was carried out from October 12, 2021, to January 6, 2022. A total of 807 surveys were collected, and the analysis included 807 completed forms that met the criteria for proper completion. The statistical analysis was performed based on the Pearson Chi
coefficient with a significance level of p<0.05.
The results obtained in the study indicate that the natural cosmetics market is intensively developing, mainly because of consumers' increasing self-awareness and deepening knowledge of cosmetics. Moreover, the demand for natural cosmetics in Poland will continue to develop steadily in the coming years. Currently, the quality of a cosmetic is more important to consumers than its price. Internet sales channels are developing intensively, and Influencers and recommendations of products by friends and family are the most effective way of promotion.
Significant changes in consumer attitudes toward the cosmetics market (after the COVID-19 pandemic outbreak) have been observed. From the manufacturers' perspective, it is advised to closely follow market trends and adapt to consumers' changing preferences and requirements. An adequate solution is to popularise and develop the segment of natural cosmetics using various forms of promotion and distribution of products. Further research is recommended to confirm the results regarding the significance of the fast-growing natural cosmetics market in Poland and other countries.
How did powder and paint, once scorned as immoral, become indispensable to millions of respectable women? How did a "kitchen physic," as homemade cosmetics were once called, become a ...multibillion-dollar industry? And how did men finally take over that rarest of institutions, a woman's business? InHope in a Jar, historian Kathy Peiss gives us the first full-scale social history of America's beauty culture, from the buttermilk and rice powder recommended by Victorian recipe books to the mass-produced products of our contemporary consumer age. She shows how women, far from being pawns and victims, used makeup to declare their freedom, identity, and sexual allure as they flocked to enter public life. And she highlights the leading role of white and black women-Helena Rubenstein and Annie Turnbo Malone, Elizabeth Arden and Madame C. J. Walker-in shaping a unique industry that relied less on advertising than on women's customs of visiting and conversation. Replete with the voices and experiences of ordinary women,Hope in a Jaris a richly textured account of the ways women created the cosmetics industry and cosmetics created the modern woman.
A large number of emerging contaminants (ECs) are known to persist in surface waters, and create pressure on wastewater treatment works (WWTW) for their effective removal. Although a large database ...for the levels of these pollutants in water systems exist globally, there is still a lack in the correlation of the levels of these pollutants with possible long-term adverse health effects in wildlife and humans, such as endocrine disruption. The current study detected a total of 55 ECs in WWTW influent surface water, 41 ECs in effluent, and 40 ECs in environmental waters located upstream and downstream of the plant. A list of ECs persisted through the WWTW process, with 28% of all detected ECs removed by less than 50%, and 18% of all ECs were removed by less than 25%. Negative mass balances of some pharmaceuticals and metabolites were observed within the WWTW, suggesting possible back-transformation of ECs during wastewater treatment. Three parental illicit drug compounds were detected within the influent of the WWTW, with concentrations ranging between 27.6 and 147.0 ng L−1 for cocaine, 35.6–120.6 ng L−1 for mephedrone, and 270.9–450.2 ng L−1 for methamphetamine. The related environmental risks are also discussed for some ECs, with particular reference to their ability to disrupt endocrine systems. The current study propose the potential of the pharmaceuticals carbamazepine, naproxen, diclofenac and ibuprofen to be regarded as priority ECs for environmental monitoring due to their regular detection and persistence in environmental waters and their possible contribution towards adverse health effects in humans and wildlife.
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•A list of ECs and metabolites persist in the aqueous phase of surface waters.•High levels of illicit drugs in wastewater indicates drug abuse within the area of study.•Conjugate or metabolites of PPCPs might be back-transformed during WWTW processes.•Persistent ECs may accumulate in WWTW effluent, leading to environmental risk.•Concentrations of ECs in surface waters provide a link towards possible endocrine disruption within aquatic vertebrates.
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