Since times immemorial, many plant species have been utilized to cure severe diseases. A wide range of diversification has been observed in various medicinal plants, which are indeed able to cure ...several deadly diseases. The presence of secondary metabolites is a high priority for their medicinal characteristics. This study focused on T. stans (Yellow bells), a shrub that grows profoundly in tropical and sub-tropical regions. Although many studies have been done on the medicinal value of this plant, not much has been done on cancer treatment and nanomedicine. Green synthesized silver nanoparticles are an eco-friendly approach to delivering the drug to the target size. Nano appearance is an add-on advantage of these compounds. Hence, it is emerging in medicine. Colorectal cancer is the fourth deadliest one globally. Hence the synthesized silver nanoparticles of T. stans flower and leaf extracts showed cytotoxically and wound healing properties on colorectal cancer cell lines (HCT 116 and SW 480). Synthesis of silver nanoparticles confirmation is done by Ultra Violet Visible spectrophotometry and Particle size analyzer. All the results showcase the beneficial effects of silver nanoparticles synthesized plant extracts and may be used as a novel medicine in the field of chemotherapy.
Many plant extracts and essential oils show antibacterial and antifungal activities, with potential to replace the use of synthetic fungicides. We used invasive alien plants goldenrod (
spp.) and ...Japanese knotweed (
) as source materials to determine their antifungal activities against seed-associated fungi from wheat grain (
and
).
Aqueous and organic extracts (ethanol, methanol and acetone) were prepared from leaves and flowers of
,
and
, and leaves and rhizomes of
. Additionally, essential oils were distilled from
flowers and leaves. The extracts and essential oils were tested as inhibitors of fungal growth
.
essential oils were tested also as antifungal agents for protection of wheat grain by determining its fungal infection and germination rate.
The extracts showed a wide spectrum of low to moderate antifungal activities, with those of
spp. generally more effective than those of
, and organic extracts more effective than aqueous extracts. The essential oils from leaves and flowers had similar antifungal activity and whole shoots can be collected for their production. This study presents the systematic study of the composition of essential oils from flowers and leaves of three widely distributed
spp. in Slovenia, with the major constituents of terpenes and terpenoids α-pinene, germacrene D and bornyl acetate.
The study presents the first use of
spp. and
extracts and essential oils against fungal strains isolated from wheat grain.
Antifungal, antimicrobial, insecticidal and antioxidant activities of Origanum vulgare L. provide the basis for suggesting that oregano plant extracts may be useful for prevention and treatment of ...infections. The main goal of this study was to determine antimicrobial and antioxidant activities of methanolic and aqueous extracts of the leaves and flowers of O. vulgare. Antimicrobial testing of plant extracts was done using well diffusion method. Activity of extracts was tested against Gram positive bacteria: Staphylococcus aureus ATCC 25923, methicillin-resistant Staphylococcus aureus (MRSA) ATCC 33591, Bacillus subtilis ATCC 6633, Enterococcus faecalis ATCC 29212 and five Gram-negative bacteria: Salmonella abony ATCC 6017, Salmonella enterica serovar Enteritidis ATCC 31194, Pseudomonas aeruginosa ATCC 9027, Escherichia coli ATCC 25922, extended-spectrum β-lactamase (ESBL) producing Escherichia coli ATCC 35218 and fungus Candida albicans ATCC 1023. Antibiotic ampicillin and antimycotic nystatin were used as positive control. The antioxidant activity was determined using the DPPH (1,1-diphenyl-2-picrylhydrazyl) method. The highest values for inhibition zone for methanolic and aqueous extracts were recorded for Gram positive B. subtilis, S. aureus and MRSA. Methanolic extracts exhibited antibacterial activity against tested Gram negative bacteria in variable degree while the growth of these bacteria was not inhibited by aqueous extracts. Tested fungus C. albicans was not sensitive to investigated oregano extracts. All the extracts showed moderate to potent antioxidant activity with methanolic flower extract demonstrating the strongest antioxidative activity with the IC50 value of 0.205 mg/mL. Therefore it can be concluded that flower and leaf oregano extracts have significant antibacterial and antioxidant potential.
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