Lysosomal storage disorders (LSDs) are a clinically heterogeneous group of more than 50 disorders which still represent a challenge in modern medicine. The efficacy of many current and proposed ...therapies relies heavily upon early detection and treatment prior to the onset of irreversible pathology. Although there are multiple paths and algorithms to a final diagnosis, the diagnostic strategy for LSDs still mostly relies on initial clinical suspicion followed by adequate specialist and laboratory management - a selective screening approach. Despite the fact that the technology of tandem mass spectrometry enables newborn screening, such screening is generally acceptable only for a population at high risk for a certain LSD. As diagnostic testing for these disorders may be difficult, communication between the clinician who has established clinical suspicion and laboratory personnel will help complete this process.
Poremećaji u skladištenju lizozoma u kliničkom smislu čine heterogenu grupu više od 50 poremećaja koji još pred stavljaju izazov za modernu medicinu. Efikasnost mnogih postojećih i predloženih terapija u velikoj meri zavisi od rane detekcije i primene terapije pre nego što dođe do razvoja neizle čive patologije. Iako postoje brojni putevi i algoritmi za konačnu dijagnozu, dijagnostička strategija za poremećaje u skladištenju lizozoma i dalje se uglavnom oslanja na početnu kliničku sumnju posle koje sledi adekvatan specijalistički tretman i laboratorijski radpristup selektivnog skrininga. Uprkos činjenici da tehnologija tandem masene spektrometrije omogućava skrining novorođenčadi, takav skrining je generalno prihvatljiv samo za populacije sa visokim rizikom za odre đeni poremećaj u skladištenju lizozoma. Kako dijagnostič ko testiranje za ove poremećaje može biti teško, komunikacija između kliničara koji je ustanovio kliničku sumnju i osoblja u laboratoriji doprineće uspešnom okončanju ovog procesa.
Provider: - Institution: Koroška osrednja knjižnica dr. Franca Sušnika - Data provided by Europeana Collections- Predstavniki Univerze v Ljubljani, Biotehniške fakultete in Oddelka za gozdarstvo ...podpišejo v navzočnosti ustanoviteljice Slovesno izjavo ob ustanovitvi Pahernikove ustanove.Od leve proti desni prof. dr. Dušan Mlinšek, akad. prof. dr. Alenka Šelih, tedanji rektor Univerze v Ljubljani prof. dr. Jože Mencinger, ustanoviteljica Pahernikove ustanove Vida Ribnikar in inž. gozdarstva ter kasneje predsednik uprave Pahernikove ustanove Maks Sušek.- All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Z denarnimi sredstvi je poskrbel za delovanje šole v Šentvidu. Bil je znani izdelovalec klavirjev, ki so jim nekdaj rekli ...glasovirji. Po njem se imenuje cesta blizu stanovanjskega naselja Podgora. - All metadata published by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
Provider: - Institution: - Data provided by Europeana Collections- Ustanovitev Vdovskega in sirotinskega pomožnega zaklada, da bi pomagali vdovam in sirotam padlih vojakov. - All metadata published ...by Europeana are available free of restriction under the Creative Commons CC0 1.0 Universal Public Domain Dedication. However, Europeana requests that you actively acknowledge and give attribution to all metadata sources including Europeana
L'articolo esamina il mistero dell'incarnazione nei testi dei Padri che commentano espressamente soltanto tutto il Simbolo Apostolico. Tralascia, perció, quelle opere patristiche che espongono la ...fede come tale, o spiegano solamente alcune verita di essa.
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