Spontaneous intestinal perforation (SIP) is one of the most serious surgical bowel conditions affecting preterm infants. There are limited data on the mortality and morbidities of very preterm ...infants VPIs, <32 weeks' gestational age (GA) with SIP in China. The study aimed to describe the prevalence, treatment, and outcomes of SIP among VPIs in China.
This retrospective cohort study included all infants born at 24
-31
weeks GA from January 1, 2019, to December 31, 2020, and admitted within seven days after birth to the neonatal intensive care units in the Chinese Neonatal Network. The primary outcome was survival without major morbidities. The association between SIP and neonatal outcomes was evaluated using multivariate logistic regression controlling for possible confounders.
Out of the 15,814 enrolled infants, 150 (1.0%) developed SIP with a median onset age of four (IQR 2-6) days. Infants with GA 24
-25
weeks had the highest incidence of SIP (13/532, 2.4%), followed by those with GA 26
-27
weeks (22/2,005, 1.1%), 28
-29
weeks (44/5,269, 0.8%) and 30
-31
weeks (71/8,008, 0.9%). Ten SIP cases were lost to follow-up with unknown survival status and 41 (29.3%) of the remaining 140 infants with SIP died during hospitalization. Only 29.3% of infants with SIP survived without major morbidities, significantly lower than those without SIP (59.2%; P<0.01). Multivariate analysis revealed SIP was associated with a higher risk of overall death (adjusted OR 3.36; 95% CI: 1.85 to 6.08), late-onset sepsis (adjusted OR 2.10; 95% CI: 1.02 to 4.31), and bronchopulmonary dysplasia (adjusted OR 2.49; 95% CI: 1.44 to 4.30). Among all infants with SIP, 28 (18.7%) did not receive any surgical intervention. Laparotomy was provided to 113 (92.6%) of the remaining 122 infants, solely (84/122, 68.9%) or following peritoneal drainage (29/122, 23.8%), while nine (7.4%) infants underwent peritoneal drainage only.
Around 1% of VPIs in China developed SIP, associated with increased risk of mortality and morbidities. Over 90% of VPIs with SIP underwent laparotomy as initial or subsequent surgical treatment. Effective and evidence-based strategies are needed for the prevention and management of SIP.
The role of surveying in the construction of less demanding construction works was defined in more detail with the adoption of the new legislation. The surveyor is present in all stages, i.e. before, ...during and after the construction of a building, which is actually from the time the land is purchased and until the operating permit is obtained and the building is entered into official records. The paper presents in detail the surveying procedures, from parcelling, setting-out, laying out the elaboration of the surveying plan of the new situation, as well as entering the less demandingconstruction into official records. The procedures of obtaining approvals and permits are complicated and time consuming, and the role of the surveyor is, despite the designation of many responsible tasks, often an unrecognisable one.
Vpis Franza in Camille Kokoschinegg, starih staršev Hermana Potočnika po materini strani, v glavno zemljiško knjigo Magistrata Maribor, Graško predmestje. 10. marec 1850. Pokrajinski arhiv Maribor. ...Glavna zemljiška knjiga Magistrata Maribor, Graško predmestje, ok. 1820–ok. 1885.
