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  • Uporaba selektivnih inhibitorjev ponovnega privzema serotonina v razvojnem obdobju = Serotonin selective reuptake inhibitors use in children and adolescents
    Gregorič Kumperščak, Hojka
    Background. Serotonine selective reuptake inhibitors (SSRI) are relatively newantidepressants. In terms of use they are not just limited to the treatmentof depression in adults, but have broader ... indications such as obsessive-compulsive disorders (OCD) and eating disorders. In addition they are administered in the treatment of children and adolescents disorders, even though studies and clinical experience is more sparse than in adults. With oneexception, SSRI are not registered for the treatment of children and adolescents, even though they are second most commonly prescribed psychotropicmedications in this age group. This article summarizes published clinical experience with SSRI in the treatment of children and adolescents. A short comparison of pharmacodynamics, pharmacokinetics and SSRIs side effects in adults, children and adolescents is given. Also discussed is labeling issueconcerning the prescribing SSRIs in this age group. Conclusions. The reports described clinical effects of treatment with SSRIs, mostly benefits, for 13 indications. The most convincing evidence for efficacy for SSRIs in adolescents exists for treatment of depression and OCD. Only sparse evidence, mostly anecdotical, exists for SSRI efficacy in other conditions. Sertraline was recently registered for treatment of OCD in 6-17-year-olds in Slovenia.
    Vir: Zdravniški vestnik : glasilo Slovenskega zdravniškega društva = Slovenian medical journal = journal of Slovenian Medical Association. - ISSN 1318-0347 (Letn. 69, št. 10, oktober 2000, str. 683-687)
    Vrsta gradiva - članek, sestavni del ; neleposlovje za odrasle
    Leto - 2000
    Jezik - slovenski
    COBISS.SI-ID - 12462297

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