DIKUL - logo
(UL)
  • Polydipsia as another mechanism of hyponatremia after 'ecstasy' (3,4 methyldioxymethamphetamine) ingestion
    Brvar, Miran ...
    Acute symptomatic hyponatremia after ecstasy (3,4 methyldioxymethamphetamineč MDMA) ingestion is well documented and has been attributed to the syndrome of inappropriate antidiuretic hormone (SIADH). ... We report the case of an 18-year-old woman who took five tablets of ecstasy in a suicide attempt and drank 1700 ml water at the Emergency Department (ED). The laboratory findings obtained 5 h after ingestion showed a serum sodium concentration of 130 mmolžl, plasma osmolality of 264 mOsmžkg, urinary osmolality of 335 mOsmžkg and natriuresis of 101 mmolžl. The plasma arginine vasopressin level by radioimmunoassay was 33.7 pmolžl 5 h after ingestion. A gas chromatography-mass spectrometry assay confirmed MDMA in blood samples, with serum concentrations of 0.87 mgžl on arrival. This case report strongly suggests that MDMA reduces serum sodium levels through the dual pathways of SIADH and polydipsia. Accordingly, we believe that hyponatremia may be prevented in ED patients after MDMA ingestion by the early restriction of water intake.
    Vir: European journal of emergency medicine. - ISSN 0969-9546 (Vol. 11, no. 5, 2004, str. 302-304)
    Vrsta gradiva - članek, sestavni del
    Leto - 2004
    Jezik - angleški
    COBISS.SI-ID - 1588593

vir: European journal of emergency medicine. - ISSN 0969-9546 (Vol. 11, no. 5, 2004, str. 302-304)

loading ...
loading ...
loading ...