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  • Otroci mater z epilepsijo = Children born to mothers with epilepsy
    Kornhauser-Cerar, Lilijana, 1958- ; Blejec, Tanja ; Čebular, Boštjan
    Although the majority of children born to women with epilepsy are normal, these children are at increased risk of both anatomic and cognitive impairments. Although the exact mechanism of these ... effects remains to be delineated, current evidence suggests that they may result from in utero antiepileptic drug exposure combined with increased seizure frequency during pregnancy and genetic predisposition. Potential adverse outcomes in children include fetal loss and perinatal death, preterm birth and low birth weight, dysmorphisms and major congenital malformations, neonatal hemorrhage and withdrawal symptoms, and postnatal developmental delay or behaviour disorders.All older anticonvulsant drugs have been associated with the increased risk of adverse outcomes, yet most of these drugs do not produce anyspecific pattern of malformations. The number of reported exposed pregnancies with new antiepileptic drugs is not yet large enough to exclude the increased risk of adverse outcomes in children. Careful planning and management of pregnancy and birth by a team of neurologists, gynecologists, obstetricians, and pediatricians is essential to increase the likelihood of a healthy outcome for the mother and infant.
    Vir: Nevrološke bolezni in nosečnost (Letn. 44, suppl. 3, 2005, str. 13-17)
    Vrsta gradiva - prispevek na konferenci
    Leto - 2005
    Jezik - slovenski
    COBISS.SI-ID - 19858393

vir: Nevrološke bolezni in nosečnost (Letn. 44, suppl. 3, 2005, str. 13-17)

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