Vloga adrenergičnih receptorjev alfa pri mikrocirkulacijskem odgovoru kože na hlad in zažem arterij : disertacija
Cankar, Ksenija, 1965-
Clinically most often used methods for evaluation of the microcirculatory function are response to cold and to arterial occlusion. Both responses are complex in nature. They are composed of several ...either local or systemic components. Their roles have not been clarified yet. According to the previousstudies, there is an unsolved question on the contribution of the sympathetic nervous system acting thru the alpha1 and alpha2 adrenergic receptors. Our aim was to clarify the role of these receptors in the origin ofboth microcirculatory responses with the use of the laser-Doppler method forskin flow measurements. In the first part of the study we compared responses to the direct and indirect (the cooling of contralateral hand) localcooling before and after intradermal injection of the alpha-adrenoceptor antagonists and agonists with the response in the denervated replanted fingers. In the second part we compared cutaneous postocclusive reactive hyperaemia (PRH before and after intradermal injection of the alpha-adrenoceptor antagonists and agonists. METHODSČ Laser-Doppler (LD) flow measurements were performed on the fingertips of healthy volunteers and of patients with replanted digits. LD flow was monitored 2 minutes before and 6 minutes during local cooling of one hand at 15 degrees Celsius and before and after an 8-minute occlusion of digital arteries. In healthy fingers, we studied the effect of intradermal microinjection (1 micro l) of alpha antagonists (prazosine, yohimbine) and alfa agonists (phenilephrine, clonidine) on local cooling and PRH responses. We evaluated the degree of the LD flow decrease in response to the direct and indirect local cooling with respect to the values obtained before cooling (ANOVA, Dunnet t-test). We analysed the magnitude of peak flow of PRH and its duration. (Abstract truncated at 2000 characters).
Vrsta gradiva - disertacija
; neleposlovje za odrasle
Založništvo in izdelava - Ljubljana : [K. Cankar], 2000
Bibliografsko gradivo je bilo uspešno dodano na polico.
Dodajanje bibliografskega gradiva na polico ni uspelo.
Gradivo je že na polici.
Trajna povezava
URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto
Faktor vpliva
Izdaja
Kategorija
Razvrstitev
JCR
SNIP
JCR
SNIP
JCR
SNIP
JCR
SNIP
Izberite knjižnično izkaznico:
Baze podatkov,
v katerih je revija indeksirana
Ime baze podatkov
Področje
Leto
Povezave do osebnih bibliografij avtorjev
Povezave do podatkov o raziskovalcih v sistemu SICRIS
Storitev za pridobivanje naslova trenutno ni dostopna, prosimo, poskusite še enkrat.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrano prevzemno mesto in naslov za dostavo ter dokončali postopek rezervacije.
S klikom na gumb "V redu" boste potrdili zgoraj izbrani naslov za dostavo in dokončali postopek rezervacije.
Obvestilo
Trenutno je storitev za avtomatsko prijavo in rezervacijo nedostopna. Gradivo lahko rezervirate sami na portalu Biblos ali ponovno poskusite tukaj kasneje.
Citiranje
Funkcionalnost trenutno ni na voljo. Prosimo, poskusite kasneje.
