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  • The role of hydroxysteroid dehydrogenases in man and in microorganisms
    Žakelj-Mavrič, Marija
    Hydroxysteroid dehydrogenases (HSD) are involved in the biosynthesis of steroid hormones in classical steroidogenic tissues. In addition, HSD are important in peripheral target tissues, where they ... regulate intracellular concentrations of active steroid signalling molecules. HSD can be found in microorganisms, in bacteria, and fungi. Although their role in microbial cells is not yet quite clear, our results indicate that 17 beta-hydroxysteroid dehydrogenase (17 beta-HSD) from the fungus Cochliobolus lunatus might be involved in the regulation of intracellular testosterone concentrations. The study of microbial and especially fungal HSD is promising as the results might help to elucidate the evolution of HSD and steroid hormone signalling system.
    Vir: Acta chimica slovenica. - ISSN 1318-0207 (Let. 42, št. 3, 1995, str. 363-371)
    Vrsta gradiva - članek, sestavni del
    Leto - 1995
    Jezik - angleški
    COBISS.SI-ID - 3957721

vir: Acta chimica slovenica. - ISSN 1318-0207 (Let. 42, št. 3, 1995, str. 363-371)

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