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  • Hale, Tracy K; Norris, Gillian E; Jameson, Geoffrey B; Filichev, Vyacheslav V

    ChemMedChem, September 2014, Letnik: 9, Številka: 9
    Journal Article

    New helicase assays that recognise therapeutically important G4-DNA structures will lead to the discovery of novel molecular entities that bind not only to G4-tetrads, but also to grooves and loops of G4-DNA. Such assays can also provide inhibitors of G4-specific helicases that will shed light on the emerging involvement of helicases in cancer and other diseases linked to defective DNA repair pathways.