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Pan, Weichun; Filobelo, Luis; Pham, Ngoc D Q; Galkin, Oleg; Uzunova, Veselina V; Vekilov, Peter G
Physical review letters, 02/2009, Letnik: 102, Številka: 5Journal Article
We probe the transport properties in protein solutions stable with respect to any, solid or liquid, phase separation as a step in the understanding of transport in the cytosol of live cells. We determine the mean-squared displacement of probe particles in the time range 10;{-3}-10 s in solutions of a model protein. The tested solutions exhibit significant elasticity at high frequencies, while at low frequencies, they are purely viscous. We attribute this viscoelasticity to a dense network of weakly-bound chains of protein molecules with characteristic lifetime of 10-100 ms. The found intrinsic viscoelasticity of protein solutions should be considered in biochemical kinetics models.
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