E-viri
Recenzirano
-
Boucher, Julien; Gilbert, Caroline; Bose, Santanu; Tessier, Philippe A
The Journal of immunology (1950), 2024-May-15, Letnik: 212, Številka: 10Journal Article
The study of S100A9 in viral infections has seen increased interest since the COVID-19 pandemic. S100A8/A9 levels were found to be correlated with the severity of COVID-19 disease, cytokine storm, and changes in myeloid cell subsets. These data led to the hypothesis that S100A8/A9 proteins might play an active role in COVID-19 pathogenesis. This review explores the structures and functions of S100A8/9 and the current knowledge on the involvement of S100A8/A9 and its constituents in viral infections. The potential roles of S100A9 in SARS-CoV-2 infections are also discussed.
