Wireless power transfer (WPT) is a key technique for many existing and emerging applications in biomedical devices. This paper presents a novel implantable magnetic coupling resonate WPT system by integrating with metasurface for biological applications. The receiver element is implanted under the skin surface 3 mm and has the dual-band property for transferring power and data telemetry simultaneously. A conformal strongly coupled magnetic resonator coil is used as the transmitting coil to construct the wireless power link. In addition, we integrate the proposed WPT system with negative permeability (MNG) metasurface over the human skin surface as a miniaturized wearable device to improve the WPT efficiency. The property of the MNG and its effect on the WPT efficiency are analyzed. Considering the special implantable environment, various misalignment tolerances between the metasurface and the receiver are discussed to evaluate the coupling response of the proposed WPT system. Finally, the efficient WPT system integrating with MNG has been verified by the experimental measurements, and the measured result shows that 15.7 dB coupling enhancement can be obtained by integrating with the MNG metasurface.