The achievement of higher productivity in various sectors has been influenced by human resources that can provide quality services in order to meet the needs of customers. It is the right moment to adapt to some changes in human resources for the tourism sector. Due to the growth of the tourism industry, this study is intended to determine human resources compliance in selected large tour companies in Arusha, Tanzania. The study employs a qualitative research approach. The saturation point was reached using purposive and simple random sampling techniques. The interviews and focus group discussions (FGDs) were employed for primary data collection from the 8 key informants, representing 8 large tour companies, and 5 FGDs composed of tour guides and administrative staff from similar companies. In content analysis, the obtained data is then analyzed and thematically interpreted. The results revealed various uncomfortable human resource practices and other areas that need the restructuring of the system in place to benefit both employers and employees. Therefore, to make this successful, the study recommends that the government and potential tourism stakeholders advocate tourism development on human resources and the entire working conditions for improving the operations of tour companies.