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  • cDC1s: New Orchestrators of...
    del Fresno, Carlos; Sancho, David

    Trends in immunology, July 2019, 2019-07-00, 20190701, Letnik: 40, Številka: 7
    Journal Article

    Type-I conventional dendritic cells (cDC1s) are key in inducing adaptive immunity. Using single-cell sequencing, Ginhoux and colleagues (Immunity 2019;50:1069–1083.e8) find that a subset of activated cDC1s in bacteria-infected skin is critical for neutrophil recruitment via the production of VEGF-α. These results reveal a crucial function for cDC1s beyond antigen presentation.