Effects of 1 M NaCl on the lipid profile of detergent-resistant membranes in chloroplasts and mitochondria of salt-accumulating halophyte plants of family Amaranthaceae, Salicornia perennans Willd. and Suaeda salsa (L.) Pall. were studied. The composition of lipids and fatty acids in detergent-resistant membranes differed from total lipids of chloroplast and mitochondrial membranes by the abundance of cerebrosides and sterols. Under the given salinity level, a manyfold increase in the relative content of cerebrosides was noted in the composition of detergent-resistant chloroplast membranes of S. perennans . A similar salinity-related increase in cerebroside content was detected in detergent-resistant mitochondrial membranes of S. salsa . The opposite effect was observed for sterols: their relative content decreased under the action of salt. The results indicate that the detergent-resistant membranes are involved in the interactions of chloroplasts and mitochondria in the cell response of halophytes to salinity.