This article addresses potential effects on reflexivity of researcher’s social position (e.g. gender, age, race, immigration status, sexual orientation), personal experiences, and political and professional beliefs. Because reflexivity is a major strategy for quality control in qualitative research, understanding how it may be impacted by the characteristics and experiences of the researcher is of paramount importance. Benefits and challenges to reflexivity under three types of researcher’s position are discussed and illustrated by means of case examples: (1) reflexivity when researcher shares the experience of study participants, (2) reflexivity when researcher moves from the position of an outsider to the position of an insider in the course of the study, and (3) reflexivity when researcher has no personal familiarity or experience with what is being studied. Strategies are offered for harvesting the benefits of researcher’s familiarity with the subject and for curbing its potentially negative effects. Directions for future research are suggested.