E-viri
PDF
Recenzirano
Odprti dostop
-
Silva, Joaquim F. M. da; Garden, Simon J.; Pinto, Angelo C.
Journal of the Brazilian Chemical Society, 06/2001, Letnik: 12, Številka: 3Journal Article
Isatins (1H-indole-2,3-dione) are synthetically versatile substrates, where they can be used for the synthesis of a large variety of heterocyclic compounds, such as indoles and quinolines, and as raw material for drug synthesis. Isatins have also been found in mammalian tissue and their function as a modulator of biochemical processes has been the subject of several discussions. The advances in the use of isatins for organic synthesis during the last twenty-five years, as well as a survey of its biological and pharmacological properties are reported in this review and in the accompanying supplementary information.
