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Uehara, Anna; Tan, Chee Wah; Mani, Shailendra; Chua, Kaw Bing; Leo, Yee Sin; Anderson, Danielle E; Wang, Lin‐Fa
Journal of medical virology, April 2019, Letnik: 91, Številka: 4Journal Article
To determine whether Pteropine orthoreovirus (PRV) exposure has occurred in Singapore, we tested 856 individuals from an existing serum panel collected from 2005‐2013. After an initial screen with luciferase immunoprecipitation system and secondary confirmation with virus neutralization test, we identified at least seven individuals with specific antibodies against PRV in both assays. Our findings confirm that PRV spillover into human populations is relatively common in this region of the world.
