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  • Response to letter regardin...
    José‐López, Roberto; Gutierrez‐Quintana, Rodrigo; Pumarola, Martí; Fuente, Cristian; Añor, Sonia; Manzanilla, Edgar G.; Suñol, Anna; Pi Castro, Dolors; Sánchez‐Masian, Daniel; Fernández‐Flores, Francisco; Marioni‐Henry, Katia; Matiasek, Lara A.; Matiasek, Kaspar; Ricci, Emanuele

    Journal of veterinary internal medicine, September/October 2022, 2022-09-00, 20220901, 2022-09-01, Letnik: 36, Številka: 5
    Journal Article

    ...liberally comparing outcomes and survival after radiotherapy in dogs with unconfirmed glioma with surgery in histologically confirmed cases 5 is not accurate and could mislead readers. By contrast, a subsequently published study including 33 gliomas, all treated with surgical resection and immunotherapy, identified astrocytomas and low-grade tumors were associated with increased survival. 8 Whereas the latter study findings result from univariable analysis ours resulted from univariable followed by multivariable Cox proportional hazard modeling. ...differences between both studies' findings might be attributable to methodology of statistical analysis and lack of homogeneity of treatment modalities. ...evidence based on larger case numbers and multivariable statistical analysis is necessary to confirm any association between glioma type or grade and prognosis in dogs. ...we take this opportunity once again to invite researchers to contribute to the creation of a mutually accessible international multicenter database to better enable evidence-based research in the field of canine glioma.