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  • Coupling an individual adap...
    Yan, Qinling; Cheke, Robert A.; Tang, Sanyi

    Statistics in medicine, 28 February 2023, Letnik: 42, Številka: 5
    Journal Article

    Past seasonal influenza epidemics and vaccination experience may affect individuals' decisions on whether to be vaccinated or not, decisions that may be constantly reassessed in relation to recent influenza related experience. To understand the potentially complex interaction between experience and decisions and whether the vaccination rate is likely to reach a critical coverage level or not, we construct an adaptive‐decision model. This model is then coupled with an influenza vaccination dynamics (SIRV) model to explore the interaction between individuals' decision‐making and an influenza epidemic. Nonlinear least squares estimation is used to obtain the best‐fit parameter values in the SIRV model based on data on new influenza‐like illness (ILI) cases in Texas. Uncertainty and sensitivity analyses are then carried out to determine the impact of key parameters of the adaptive decision‐making model on the ILI epidemic. The results showed that the necessary critical coverage rate of ILI vaccination could not be reached by voluntary vaccination. However, it could be reached in the fourth year if mass media reports improved individuals' memory of past vaccination experience. Individuals' memory of past vaccination experience, the proportion with histories of past vaccinations and the perceived cost of vaccination are important factors determining whether an ILI epidemic can be effectively controlled or not. Therefore, health authorities should guide people to improve their memory of past vaccination experience through media reports, publish timely data on annual vaccination proportions and adjust relevant measures to appropriately reduce vaccination perceived cost, in order to effectively control an ILI epidemic.