E-viri
Recenzirano
-
Baneshi, Marzieh; Dadfarnia, Shayessteh; Haji Shabani, Ali Mohammad; Sabbagh, Seyyed Kazem; Bardania, Hassan
Journal of the Iranian Chemical Society, 06/2022, Letnik: 19, Številka: 6Journal Article
A pH-sensitive nano-graphene oxide (nGO)-based delivery system is designed for Cur delivery to MCF cancerous cells. Cur is loaded on the synthesized nGO (Cur-nGO) and decorated by bovine serum albumin (BSA) to improve its biostability, protect the Cur from undesired loss and provide the carboxylic functional groups for aptamer conjunction (Cur-nGO-BSA). Finally, the Cur-nGO-BSA was functionalized with AS1411 aptamer and characterized by various methods. The drug loading and loading efficiency of the designed system are 8.9% and 78.9%, respectively. The loaded drug is preferably released in acidic media at in-vitro studies. The MTT test on MCF7 as positive and SKBR3 as negative nucleolin cancer cells revealed that the Cur-nGO-BSA can inhibit their growth while AS1411 aptamer-functionalized nano-carrier showed an improved efficiency toward MCF7 cells due to the significant affinity of the aptamer toward the highly expressed nucleolin on the MCF7 plasma membrane.
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.