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Nishikawa, Tadateru; Ishiyama, Noboru; Wang, Feng; Ikura, Mitsuhiko
Biomolecular NMR assignments, 04/2017, Letnik: 11, Številka: 1Journal Article
α-Catenin is a filamentous actin (F-actin) binding protein that links the classical cadherin–catenin complex to the actin cytoskeleton at adherens junctions (AJs). Its C-terminal F-actin binding domain is required for regulating the dynamic interaction between AJs and the actin cytoskeleton during tissue development. Thus, obtaining the molecular details of this interaction is a crucial step towards understanding how α-catenin plays critical roles in biological processes, such as morphogenesis, cell polarity, wound healing and tissue maintenance. Here we report the backbone atom ( 1 H N , 15 N, 13 C α , 13 C β and 13 C′) resonance assignments of the C-terminal F-actin binding domain of αN-catenin.
