Iron is an essential micronutrient. The majority of iron in the body is used for the production of heme in erythrocytes; however, in the developing neonatal brain, it also plays keys roles in synaptogenesis, neurotransmitter production, and myelination 1 . Iron deficiency during critical periods of brain development has been associated with adverse neurodevelopmental outcomes in both preclinical models of iron deficiency 2 and in clinical studies 3 . These neurodevelopmental outcomes may be irreversible despite achieving later iron sufficiency with iron supplementation 3 . Maintaining iron sufficiency for neonates in the neonatal intensive care unit is therefore recognized as an essential part of neonatal neurocritical care.