The purpose of the study was to evaluate the radiation dose in High-Definition Reference Korean-Man phantom according to the lead equivalent in the protection devices using MCNPX. The tube voltage and current are 80–100 kV and 15 mAs, respectively, and the exposure time is 7–10 min. The range of lead equivalent of the protection devices worn by the operator phantom is 0–0.50 mmPb with the internal of 0.05 mmPb. The radiation dose indirect calculation method, the NDD(k), and variance reduction techniques are applied. The average error rate of the absorbed dose in each organ was 12.88% at 80 kV and 7.41% at 100 kV. Among the organs, the doses by the gonads (testis) and bladder accounted for 58.91%, resulting from close proximity to the table height, the origin of the scattered radiation. In case of evenly distributed bone surfaces throughout the body, it was 25.66%. This study quantitatively reports that after 0.25 mmPb lead equivalent of radiation protection devices commonly used in the clinical interventional procedure, TACE, the decrease in effective dose begins to slow down and become constant.