E-viri
Recenzirano
Odprti dostop
-
Adam, Hamdi S.; Lakshminarayan, Kamakshi; Wang, Wendy; Norby, Faye L.; Mosley, Thomas; Walker, Keenan A.; Gottesman, Rebecca F.; Meyer, Katie; Hughes, Timothy M.; Pankow, James S.; Wong, Dean F.; Jack, Clifford R.; Sen, Souvik; Lutsey, Pamela L.; Beck, Jim; Demmer, Ryan T.
Journal of clinical periodontology, April 2022, Letnik: 49, Številka: 4Journal Article
Aim We investigate if periodontal disease is prospectively associated with cerebrovascular and neurodegenerative markers of dementia and Alzheimer's pathology. Materials and Methods N = 1306 participants (Visit 5 mean age = 76.5 standard deviation = 5.4 years) in the Atherosclerosis Risk in Communities study with completed dental exams at Visit 4 underwent brain magnetic resonance imaging scans at Visit 5 while N = 248 underwent positron emission tomography scans. Participants were classified as edentulous or, among the dentate, by the modified Periodontal Profile Class. Brain volumes were regressed on periodontal status in linear regressions. Cerebrovascular measures and β‐amyloid positivity were regressed on periodontal status in logistic regressions. Results Periodontal disease was not associated with brain volumes, microhaemorrhages, or elevated β‐amyloid. Compared with periodontally healthy individuals, odds ratios 95% confidence interval for all‐type infarcts were 0.37 0.20, 0.65 for severe tooth loss and 0.56 0.31, 0.99 for edentulous participants. Conclusions Within the limitations of this study, periodontal disease was not associated with altered brain volumes, microhaemorrhages, or β‐amyloid positivity. Tooth loss was associated with lower odds of cerebral infarcts.
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.