E-viri
Recenzirano
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Zhang, Zhen-Peng; Liu, Yan; Zou, Hai-Dan; Pan, Juan; Hao, Zhi-Chao; Guan, Wei; Algradi, Adnan Mohammed; Kuang, Hai-Xue; Yang, Bing-You
Journal of natural medicines, 2024/1, Letnik: 78, Številka: 1Journal Article
Six new naphthoquinones, euchronin A–F ( 1 – 6 ) and nine known naphthoquinones ( 7 – 15 ), were isolated from the roots of Arnebia euchroma (Royle) Johnst. The structures of the new compounds were confirmed by extensive spectroscopic analyses, including UV, IR, HR-ESI–MS, 1D and 2D NMR. In the present study, we estimated the anti-proliferative activities of these compounds with HaCaT cells. The results indicated that compounds 2 and 4 showed strong anti-proliferative activities at 25 μM, with relative viability at 38.83% and 68.44%, respectively. Graphical Abstract
