Hydropower, biomass, biogas, biofuels, wind power, solar energy and geothermal energy are the major resources to provide Backa region with most of its. Backa extends between 45°16′ and 46°22′ of the northern latitude and 18°36′ and 20°37′ of the eastern longitude. It occupies the north-eastern part of Vojvodina, i.e. the most north-western part of the Republic of Serbia. That is historical-geographic territory bordered on the Danube on its western and eastern side, the Tisa on its eastern side and with the state border towards Hungary on the north. In this paper, the focus will be on renewable sources, specifically geothermal energy in Backa region. The paper analyzes the characteristics of thermal–mineral waters in Backa, the condition and possibilities of their exploitation in spa tourism, and in other economic branches. The tradition of thermo-mineral waters exploitation in spas and public baths is rather long. Today, this type of thermo-mineral waters exploitation in Backa is the widest spread. Permanent, i.e. continuous exploiters of thermal–mineral waters in Backa are primarily balneal–rehabilitation centres and exploiters using the water for technological purposes.