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Martin, Dale D.O; Ladha, Safia; Ehrnhoefer, Dagmar E; Hayden, Michael R
Trends in neurosciences (Regular ed.), 01/2015, Letnik: 38, Številka: 1Journal Article
Highlights • HTT is an important regulator of autophagy that is, in turn, degraded by autophagy. • Genes regulating protein clearance show altered expression in HD brains. • Defining HD-specific alterations in autophagy is crucial for the development of therapeutics. • Post-translational modifications influence the role of HTT as a regulator of autophagy.
