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Flohr, Tanya R., M.D; Bonatti, Hugo, M.D; Hranjec, Tjasa, M.D; Keith, Doug S., M.D; Lobo, Peter I., M.D; Kumer, Sean C., M.D; Schmitt, Timothy M., M.D; Sawyer, Robert G., M.D; Pruett, Timothy L., M.D; Roberts, John P., M.D; Brayman, Kenneth L., M.D., Ph.D
The Journal of surgical research, 08/2012, Letnik: 176, Številka: 2Journal Article
Our institution explored using allografts from donors with Hepatitis C virus (HCV) for elderly renal transplantation (RT). Thirteen HCV– elderly recipients were transplanted with HCV+ allografts (eD+/R–) between January 2003 and April 2009. Ninety HCV– elderly recipients of HCV– allografts (eD–/R–), eight HCV+ recipients of HCV+ allografts (D+/R+) and thirteen HCV+ recipients of HCV– allografts (D–/R+) were also transplanted. Median follow-up was 1.5 (range 0.8–5) years. Seven eD+/R– developed a positive HCV viral load and six had elevated liver transaminases with evidence of hepatitis on biopsy. Overall, eD+/R– survival was 46% while the eD–/R– survival was 85% ( P = 0.003). Seven eD+/R– died during follow-up. Causes included multi-organ failure and sepsis ( n = 4), cancer ( n = 1), failure-to-thrive ( n = 1) and surgical complications ( n = 1). One eD+/R– died from causes directly related to HCV infection. In conclusion, multiple eD+/R– quickly developed HCV-related liver disease and infections were a frequent cause of morbidity and mortality.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
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Vir: Osebne bibliografije
in: SICRIS
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