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  • Diagnostic and Therapeutic ...
    Le Jemtel, Thierry H., MD; Padeletti, Margherita, MD; Jelic, Sanja, MD

    Journal of the American College of Cardiology, 01/2007, Letnik: 49, Številka: 2
    Journal Article

    Diagnostic and Therapeutic Challenges in Patients With Coexistent Chronic Obstructive Pulmonary Disease and Chronic Heart Failure Thierry H. Le Jemtel, Margherita Padeletti, Sanja Jelic Chronic obstructive pulmonary disease (COPD) may delay the diagnosis of chronic heart failure (CHF), and promote nonadherence to therapeutic guidelines, especially beta-blockade. Skeletal muscle alterations are strikingly similar in both conditions. Improvement of pulmonary or cardiac function does not translate into improved functional capacity unless skeletal muscle alterations concomitantly regress. Beta-blockade is safe in stable COPD. Beta -blockade should be attempted in all CHF patients with coexistent CHF and COPD.