E-viri
Recenzirano
-
Heller, Simon, FRCP; Darpö, Börje, MD, PhD; Mitchell, Malcolm I., MBBS, MFPM; Linnebjerg, Helle, PhD; Leishman, Derek J., PhD, DSP; Mehrotra, Nitin, PhD; Zhu, Hao, PhD; Koerner, John, PhD; Fiszman, Mónica L., MD, PhD; Balakrishnan, Suchitra, MD, PhD; Xiao, Shen, MD, PhD; Todaro, Thomas G., MD, JD; Hensley, Ingrid, PhD; Guth, Brian D., PhD; Michelson, Eric L., MD, FACC; Sager, Philip, MD, FACC, FAHA, FHRS
The American heart journal, 07/2015, Letnik: 170, Številka: 1Journal Article
Thorough QT studies conducted according to the International Council on Harmonisation E14 guideline are required for new nonantiarrhythmic drugs to assess the potential to prolong ventricular repolarization. Special considerations may be needed for conducting such studies with antidiabetes drugs as changes in blood glucose and other physiologic parameters affected by antidiabetes drugs may prolong the QT interval and thus confound QT/corrected QT assessments. This review discusses potential mechanisms for QT/corrected QT interval prolongation with antidiabetes drugs and offers practical considerations for assessing antidiabetes drugs in thorough QT studies. This article represents collaborative discussions among key stakeholders from academia, industry, and regulatory agencies participating in the Cardiac Safety Research Consortium. It does not represent regulatory policy.
Avtor
![loading ... loading ...](themes/default/img/ajax-loading.gif)
Vnos na polico
Trajna povezava
- URL:
Faktor vpliva
Dostop do baze podatkov JCR je dovoljen samo uporabnikom iz Slovenije. Vaš trenutni IP-naslov ni na seznamu dovoljenih za dostop, zato je potrebna avtentikacija z ustreznim računom AAI.
Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
---|---|---|---|---|---|---|---|---|
JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
Baze podatkov, v katerih je revija indeksirana
Ime baze podatkov | Področje | Leto |
---|
Povezave do osebnih bibliografij avtorjev | Povezave do podatkov o raziskovalcih v sistemu SICRIS |
---|
Vir: Osebne bibliografije
in: SICRIS
To gradivo vam je dostopno v celotnem besedilu. Če kljub temu želite naročiti gradivo, kliknite gumb Nadaljuj.