BSTS epitaxial thin film topological insulators were grown using the MBE technique on two different types of substrates , Si (111) and SiC/graphene with Bi Sb Te Se and Bi Sb Te Se , respectively. The crystallographic properties of BSTS films were investigated X-ray diffraction, which showed the strongest reflections from the (0 0 ) facets corresponding to the rhombohedral phase. Superior epitaxial growth, homogeneous thickness, smooth surfaces, and larger unit cell parameters were observed for the films grown on the Si substrate. Polarization dependent Raman spectroscopy showed a weak appearance of the A mode in cross--polarized geometry. In contrast, a strong E mode was observed in both parallel and cross-polarized geometries which correspond to the rhombohedral crystal symmetry of BSTS films. A redshift of A and E modes was observed in the Raman spectra of BSTS films grown on the Si substrate, compared to those on SiC/graphene, which was directly associated with the unit cell parameter and composition of the films. Raman spectra showed four fundamental modes with asymmetric line shape, and deconvolution of the peaks resulted in additional modes in both the BSTS thin films. The sum of relative ratios of linewidths of fundamental modes (A and E ) of BSTS films grown on Si substrate was lower, indicating a more ordered structure with lower contribution of defects as compared to BSTS film grown on SiC/graphene substrate.