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Pound, Elisabeth; Ashton, Jeffrey R; Becerril, Héctor A; Woolley, Adam T
Nano letters, 12/2009, Letnik: 9, Številka: 12Journal Article
Designs for DNA origami have previously been limited by the size of the available single-stranded genomes for scaffolds. Here we present a straightforward method for the production of scaffold strands having various lengths, using polymerase chain reaction amplification followed by strand separation via streptavidin-coated magnetic beads. We have applied this approach in assembling several distinct DNA nanostructures that have thin (∼10 nm) features and branching points, making them potentially useful templates for nanowires in complex electronic circuitry.
