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Li, Wen-Feng; Huang, Yu-Qing; Feng, Ying-Qing
Journal of human hypertension, 07/2019, Letnik: 33, Številka: 7Journal Article
The aim of this meta-analysis of longitudinal studies was to obtain a valid and cogent assessment of predictive value of central haemodynamic variables for cardiovascular outcomes and all-cause mortality. We searched for eligible articles using MEDLINE, CINAHL, EMBASE and Web of Science between 1 January 1969 and 31 December 2017. We finally included 24 prospective cohort studies, comprising 146,986 individuals for this analysis. Adjusted pooled hazard ratio of total cardiovascular events was 1.10 (95% confidence interval CI 1.04-1.16) for a 10 mmHg increase of central systolic pressure, 1.12 (95% CI 1.05-1.19) for a 10 mmHg increase of central pulse pressure and 1.18 (95% CI 1.09-1.27) for a 10% increase of central augmentation index. Furthermore, pooled hazard ratio of all-cause mortality was 1.22 (95% CI 1.14-1.31) for a 10 mmHg increase of central pulse pressure and 1.19 (95% CI 1.05-1.34) for a 10% increase of central augmentation index. Central haemodynamic variables are independent predictors of cardiovascular disease and all-cause mortality. This finding supports the notion that central pressure components and indices could be suitably implemented in clinical practice.
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Leto | Faktor vpliva | Izdaja | Kategorija | Razvrstitev | ||||
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JCR | SNIP | JCR | SNIP | JCR | SNIP | JCR | SNIP |
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Vir: Osebne bibliografije
in: SICRIS
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