This paper deals with the significance of traffic position of Sv. Andrija Island (Croatia; Eng. St Andrew Island) on Adriatic sailing routes. Numerous archeological findings and written historical sources indicate the importance of the route across the Adriatic from Monte Gargano on western Adriatic coast over Palagruža toward Sv. Andrija or Vis and finally to eastern Adriatic coast (and vice versa). As it could be expected, the main geographical objects of terrestrial navigation along this route were always presented on old geographic and navigational maps. Although it is a small island, Sv. Andrija was always presented on these maps, regardless of the map scale, and sometimes it was even made larger than it actually was. Such cartographic generalization, i.e. choice of items presented on the maps, indicate historical and geographical continuity of traffic valorization of Sv. Andrija and the whole eastern Adriatic maritime zone as it is obvious that geographers and cartographers of that time paid much attention to it.