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  • C-N bond forming cross-coup...
    Bariwal, Jitender; Van der Eycken, Erik

    Chemical Society reviews, 12/2013, Letnik: 42, Številka: 24
    Journal Article

    Nitrogen containing compounds are of great importance because of their interesting and diverse biological activities. The construction of the C-N bond is of significant importance as it opens avenues for the introduction of nitrogen in organic molecules. Despite significant advancements in this field, the construction of the C-N bond is still a major challenge for organic chemists, due to the involvement of harsh reaction conditions or the use of expensive catalysts in many cases. Thus, it is a challenge to develop alternative, milder and cheaper methodologies for the construction of C-N bonds. Herein, we have selected some prime literature reports that may serve this purpose. This tutorial review highlights the currently used methods for the construction of C-N bonds using various transition metal catalyst and metal-free reactions under mild reaction conditions.