•Reiki practice decreased the somatic, psychological and urogenital symptoms experienced during menopause.•It can be recommended to the clinical nurses to include the Reiki applications in the menopausal symptoms relieving intervention preferences.•Reiki practice are very important in reducing the somatic, psychological and urogenital symptoms with women in providing holistic nursing care. The present study was conducted in order to determine the effects of Reiki on the menopausal symptoms of women. This study having a randomized controlled experimental design was carried out involving 48 individuals (24 in Reiki, 24 in control). Study data were collected between November 2018 and February 2019 by using a personal information form, The Menopause Rating Scale. The mean menopausal symptoms score of women decreased after Reiki intervention and the difference was found to be statistically significant (p < 0.05). Reiki reduced the menopausal symptoms levels of women having menopause. It has been found that distant Reiki application is effective in reducing somatic, psychological and urogenital complaints in women during menopause.